Joint associations of insomnia and sleep duration with prevalent diabetes: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL).
Joint associations of insomnia and sleep duration with prevalent diabetes: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL).
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DOI：
10.1111/1753-0407.12308
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发表时间：
2016-05
影响因子：
4.5
通讯作者：
Patel SR
中科院分区：
文献类型：
--
作者：
Cespedes EM;Dudley KA;Sotres-Alvarez D;Zee PC;Daviglus ML;Shah NA;Talavera GA;Gallo LC;Mattei J;Qi Q;Ramos AR;Schneiderman N;Espinoza-Giacinto RA;Patel SR
睡眠数量和质量不足与患2型糖尿病的风险更高相关。这种关系在美国拉美裔/拉丁裔中没有得到很好的研究，之前的分析可能会因为睡眠呼吸暂停而混淆。这项横断面研究调查了不同的美国西班牙裔/拉美裔美国人中睡眠时间和失眠与糖尿病的联合关系。关于睡眠数量和质量的基线数据来自西班牙裔社区健康研究/拉美裔研究的15227名参与者(平均年龄41岁；范围为18-74岁)。采用复杂调查多项式Logistic回归分析糖尿病流行与6种表型之间的关系，这些表型通过交叉分类睡眠时间(短≤6小时，平均6-9小时，长-9小时)和失眠，调整了性别、年龄、地点和拉美裔/拉丁裔背景互动、教育、体力活动、饮食质量和睡眠呼吸暂停。在加权人群中，14%患有糖尿病，28%患有失眠，9%为短睡者，19%为长睡者。与睡眠一般且无失眠者相比，睡眠不足且失眠者患糖尿病的可能性更大(优势比[OR]1.46；95%可信区间[CI]1.02，2.11)。平均失眠者(1.28；95%可信区间1.02，1.61)和长期睡眠不失眠者(1.33；95%可信区间1.07，1.65)患糖尿病的几率也较高。对体重指数的进一步调整减弱了相关性，除了长时间睡眠而没有失眠。在西班牙裔/拉丁裔中，睡眠数量和质量的下降都与糖尿病有关，睡眠时间短和失眠的人患糖尿病的几率最大。这种联系在很大程度上可以用肥胖来解释。
Inadequate sleep quantity and quality are associated with a higher risk of type 2 diabetes. This relationship is not well-examined in US Hispanics/Latinos, and prior analyses may be confounded by sleep apnea. This cross-sectional study examined joint associations of sleep duration and insomnia with diabetes among diverse US Hispanic/Latinos. Baseline data on sleep quantity and quality were obtained from 15227 participants (mean age 41; range 18–74 years) from the Hispanic Community Health Study/Study of Latinos. Complex survey multinomial logistic regression was used to examine associations between prevalent diabetes and six phenotypes defined by cross-classifying sleep duration (short ≤6 h, average >6–9 h, long >9 h) and insomnia, adjusting for sex, age, site and Hispanic/Latino background interaction, education, physical activity, diet quality, and sleep apnea. In the weighted population, 14% had diabetes, 28% had insomnia, 9% were short sleepers, and 19% were long sleepers. Compared with those with average sleep and no insomnia, those with short sleep and insomnia were more likely to have diabetes (odds ratio [OR] 1.46; 95% confidence interval [CI] 1.02, 2.11). Average sleepers with insomnia (1.28; 95% CI 1.02, 1.61) and long sleepers without insomnia (1.33; 95% CI 1.07, 1.65) also had elevated odds of diabetes. Further adjustment for body mass index attenuated associations, except with long sleep without insomnia. Both decreased quantity and quality of sleep are associated with diabetes in Hispanic/Latinos, with the greatest odds among those with short sleep duration and insomnia. The association is largely explained by obesity.
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影响因子：
16.2
作者：
通讯作者：
--
影响因子：
5.6
作者：
Lavange, Lisa M.;Kalsbeek, William D.;Sorlie, Paul D.;Aviles-Santa, Larissa M.;Kaplan, Robert C.;Barnhart, Janice;Liu, Kiang;Giachello, Aida;Lee, David J.;Ryan, John;Criqui, Michael H.;Elder, John P.
通讯作者：
Elder, John P.
影响因子：
16.2
作者：
Cappuccio FP;D'Elia L;Strazzullo P;Miller MA
通讯作者：
Miller MA
影响因子：
5.4
作者：
Jackson, Chandra L.;Hu, Frank B.;Kawachi, Ichiro
通讯作者：
Kawachi, Ichiro
影响因子：
16.2
作者：
Ayas, NT;White, DP;Hu, FB
通讯作者：
Hu, FB