Peritoneal and hemodialysis: I. Differences in patient characteristics at initiation.

Peritoneal and hemodialysis: I. Differences in patient characteristics at initiation.
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腹膜和血液透析:I. 开始时患者特征的差异。

DOI:
10.1046/j.1523-1755.2002.00175.x
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发表时间:
2002
影响因子:
19.6
通讯作者:
Collins,AllanJ
Collins,AllanJ
中科院分区:
医学1区
文献类型:
--
作者:
Xue,JayL;Chen,Shu-Cheng;Ebben,JamesP;Constantini,EdwardG;Everson,SusanE;Frazier,EricT;Agodoa,LawrenceY;Collins,AllanJ

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腹膜透析和血液透析:I.腹膜透析(PD)和血液透析(HD)患者之间的死亡率结果的比较显示出不同的结果,这可能是由于患者在开始时的临床状况分布不均造成的。为了解决这一问题,我们利用美国1995 - 1997年医学证据表中治疗终末期肾病的发病率数据,对105,954例开始PD和HD的患者的临床特征进行了评估。方法采用一般线性模型分析年龄、白蛋白、肌酐、血尿素氮(BUN)和红细胞压积的差异;分类数据分析评估身体质量指数(BMI),分为四类:!19,19-25(!25),25-30(!30)和30+;和逻辑回归,以评估启动PD与HD的可能性。糖尿病患者(DM)与非糖尿病患者(NDM)分开分析。Logistic回归分析的解释变量包括发病年份、种族、性别、年龄、BMI、白蛋白、肌酐、BUN和红细胞压积。人种包括白色和黑色。年龄分为四组:20-44,45-64,65-74,和75+。0.0001)。PD患者也有较高的(P!0.0001)白蛋白(DM +0.35 g/dL和NDM +0.23 g/dL)和红细胞压积(DM +1.64%和NDM +1.71%)水平,以及较低(P!0.04)BUN(DM为-8.75 mg/dL,NDM为-5.24 mg/dL)和肌酐(DM为-0.51 mg/dL,NDM为-0.23 mg/dL)水平。白人有更高的(P!0.0001)的可能性开始PD比黑人,和患者的BMI!19个有较低的(P!结论PD患者在开始透析时具有良好的临床条件,在比较两种模式的透析结果时应考虑到这一点。
Peritoneal and hemodialysis: I. Differences in patient characteristics at initiation.BackgroundComparisons of mortality outcomes between peritoneal dialysis (PD) and hemodialysis (HD) patients have shown varying results, which may be caused by the unequally distributed clinical conditions of patients at initiation. To address this issue, we evaluated the clinical characteristics of 105,954 patients at the initiation of PD and HD, using the U.S. national incidence data on treated end-stage renal disease from the Medical Evidence Form, 1995 to 1997.MethodsA general linear model was used to analyze differences of age, albumin, creatinine, blood urea nitrogen (BUN), and hematocrit; categorical data analysis to evaluate body mass index (BMI), grouped into four categories: !19, 19–25 (!25), 25–30 (!30), and 30+; and logistic regression to assess the likelihood of initiating PD versus HD. Diabetics (DM) were analyzed separately from non-diabetics (NDM). Explanatory variables in the logistic regression included incidence year, race, gender, age, BMI, albumin, creatinine, BUN, and hematocrit. Race included white and black. Age was categorized into four groups: 20–44, 45–64, 65–74, and 75+.ResultsAt the initiation of dialysis PD patients were approximately 6 years younger (P! 0.0001) than HD patients. PD patients also had higher (P! 0.0001) albumin (+0.35 g/dL for DM and +0.23 g/dL for NDM) and hematocrit (+1.64% for DM and +1.71% for NDM) levels, and lower (P! 0.04) BUN (-8.75 mg/dL for DM and -5.24 mg/dL for NDM) and creatinine (-0.51 mg/dL for DM and -0.23 mg/dL for NDM) levels than HD patients. Whites had a higher (P! 0.0001) likelihood of starting PD than blacks, and patients with BMI !19 had a lower (P! 0.0001) chance of beginning on PD.ConclusionPD patients had favorable clinical conditions at the initiation of dialysis, which should be taken into consideration when comparing dialysis outcomes between the two modalities.
DOI: --
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期刊:
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关于自我监控的本质:评估问题、有效性问题。
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