RSV reemergence in Argentina since the SARS-CoV-2 pandemic.
RSV reemergence in Argentina since the SARS-CoV-2 pandemic.
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DOI：
10.1016/j.jcv.2022.105126
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发表时间：
2022-04
期刊：
影响因子：
--
通讯作者：
Mariana V
中科院分区：
文献类型：
--
作者：
Dolores A;Stephanie G;Mercedes S NJ;Érica G;Mistchenko AS;Mariana V
简介：因COVID-19疫情而采取的社区缓解措施对二零二零年最常见的呼吸道病毒的传播产生了副作用。在呼吸道合胞病毒（RSV）这一重要的儿科病原体的情况下，以前曾描述过病例数减少和延迟暴发。目的和方法：研究了COVID-19大流行之前和期间阿根廷布宜诺斯艾利斯儿科患者中RSV循环毒株的遗传特征。通过G基因测序和进化分析，分析了从呼吸道感染住院患者（2018- 2021年）中采集的RSV（+）样本。结果如下：于二零二零年，布宜诺斯艾利斯并无录得因呼吸道合胞病毒住院的儿科患者;然而，呼吸道合胞病毒于二零二一年再度出现，病例数目减少，疫情延迟爆发，于七月至八月达到高峰。共分析了147个G基因序列。2018年和2021年，RSV-B（N = 85）占主导地位，而2019年，RSV-A更普遍（N = 62）。所有RSV-A序列均为ON 1样株，所有RSV-B序列均为BA样株。系统发育分析表明，在2020年之前和之后传播的遗传谱系相同，但2021年的RSV对应于新的病毒引入，而不是2020年期间布宜诺斯艾利斯先前遗传簇的神秘传播。结论：随着边境重新开放，RSV在阿根廷的重新出现带来了来自其他国家的新病毒传入。因此，重要的是继续对大流行后循环中的RSV毒株进行深入的全球分子监测，这对未来的疫苗实施产生影响。
Introduction: The community mitigation measures taken because of the COVID-19 pandemic had side effects on the circulation of the most frequent respiratory viruses during 2020. In the case of respiratory syncytial virus (RSV), an important paediatric pathogen, a decrease in the number of cases and delayed outbreaks was previously described. Aim and Methods: The genetic characteristics of the RSV circulating strains in paediatric patients in Buenos Aires, Argentina before and during the COVID-19 pandemic were studied. RSV (+) samples taken from hospitalised patients with respiratory tract infections (2018- 2021) were analysed through G gene sequencing and evolutionary analyses. Results: No RSV hospitalised paediatric patients were registered in Buenos Aires during 2020; however, RSV reemerged in 2021 with a lower number of cases and a delayed outbreak, peaking in July-August. A total of 147 G gene sequences were analysed. RSV-B (N = 85) predominated during 2018 and 2021 whereas in 2019 RSV-A were more prevalent (N = 62). All RSV-A sequences were ON1-like strains, and all RSV-B were BA-like. Phylogenetic analyses showed that the same genetic lineages circulated before and after 2020, but RSVs from 2021 corresponded to new viral introductions rather than cryptic circulation of the previous genetic clusters in Buenos Aires during 2020. Conclusions: Following the reopening of borders, the reemergence of RSV in Argentina brought new viral introductions from other countries. Therefore, it is important to continue a deep global molecular surveillance to characterise RSV strains in post-pandemic circulation with an impact in future vaccine implementation.
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影响因子：
9.4
作者：
Tabor DE;Fernandes F;Langedijk AC;Wilkins D;Lebbink RJ;Tovchigrechko A;Ruzin A;Kragten-Tabatabaie L;Jin H;Esser MT;Bont LJ;Abram ME;INFORM-RSV Study Group
通讯作者：
INFORM-RSV Study Group
影响因子：
3.2
作者：
Viegas, M.;Goya, S.;Mistchenko, A. S.
通讯作者：
Mistchenko, A. S.
影响因子：
10.7
作者：
Nguyen LT;Schmidt HA;von Haeseler A;Minh BQ
通讯作者：
Minh BQ
DOI：
10.1016/s0140-6736(17)30938-8
发表时间：
2017-09-02
期刊：
Lancet (London, England)
影响因子：
--
作者：
Shi T;McAllister DA;O'Brien KL;Simoes EAF;Madhi SA;Gessner BD;Polack FP;Balsells E;Acacio S;Aguayo C;Alassani I;Ali A;Antonio M;Awasthi S;Awori JO;Azziz-Baumgartner E;Baggett HC;Baillie VL;Balmaseda A;Barahona A;Basnet S;Bassat Q;Basualdo W;Bigogo G;Bont L;Breiman RF;Brooks WA;Broor S;Bruce N;Bruden D;Buchy P;Campbell S;Carosone-Link P;Chadha M;Chipeta J;Chou M;Clara W;Cohen C;de Cuellar E;Dang DA;Dash-Yandag B;Deloria-Knoll M;Dherani M;Eap T;Ebruke BE;Echavarria M;de Freitas Lázaro Emediato CC;Fasce RA;Feikin DR;Feng L;Gentile A;Gordon A;Goswami D;Goyet S;Groome M;Halasa N;Hirve S;Homaira N;Howie SRC;Jara J;Jroundi I;Kartasasmita CB;Khuri-Bulos N;Kotloff KL;Krishnan A;Libster R;Lopez O;Lucero MG;Lucion F;Lupisan SP;Marcone DN;McCracken JP;Mejia M;Moisi JC;Montgomery JM;Moore DP;Moraleda C;Moyes J;Munywoki P;Mutyara K;Nicol MP;Nokes DJ;Nymadawa P;da Costa Oliveira MT;Oshitani H;Pandey N;Paranhos-Baccalà G;Phillips LN;Picot VS;Rahman M;Rakoto-Andrianarivelo M;Rasmussen ZA;Rath BA;Robinson A;Romero C;Russomando G;Salimi V;Sawatwong P;Scheltema N;Schweiger B;Scott JAG;Seidenberg P;Shen K;Singleton R;Sotomayor V;Strand TA;Sutanto A;Sylla M;Tapia MD;Thamthitiwat S;Thomas ED;Tokarz R;Turner C;Venter M;Waicharoen S;Wang J;Watthanaworawit W;Yoshida LM;Yu H;Zar HJ;Campbell H;Nair H;RSV Global Epidemiology Network
通讯作者：
RSV Global Epidemiology Network
影响因子：
4.6
作者：
Agoti, Charles N.;Phan, My V. T.;Nokes, D. James
通讯作者：
Nokes, D. James