Childhood adversities and post-traumatic stress disorder: evidence for stress sensitisation in the World Mental Health Surveys.
Childhood adversities and post-traumatic stress disorder: evidence for stress sensitisation in the World Mental Health Surveys.
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DOI：
10.1192/bjp.bp.116.197640
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发表时间：
2017-11
期刊：
影响因子：
--
通讯作者：
Kessler RC
中科院分区：
文献类型：
--
作者：
McLaughlin KA;Koenen KC;Bromet EJ;Karam EG;Liu H;Petukhova M;Ruscio AM;Sampson NA;Stein DJ;Aguilar-Gaxiola S;Alonso J;Borges G;Demyttenaere K;Dinolova RV;Ferry F;Florescu S;de Girolamo G;Gureje O;Kawakami N;Lee S;Navarro-Mateu F;Piazza M;Pennell BE;Posada-Villa J;Ten Have M;Viana MC;Kessler RC
尽管众所周知，童年时期的逆境可以预测创伤经历后患创伤后应激障碍（PTSD）的风险增加，但目前尚不清楚这种关联是否因童年逆境或创伤经历类型或年龄而异。根据童年逆境类型、创伤经历类型和生命历程阶段，研究童年逆境与创伤后应激障碍 (PTSD) 关联的变化。流行病学数据分析来自世界心理健康调查（n = 27 017）。四种童年逆境（身体虐待和性虐待、忽视、父母精神病理学）与创伤经历后患 PTSD 的几率增加相关（比值比 (OR) = 1.8），而评估的其他八种童年逆境并不能预测 PTSD。童年逆境与创伤后应激障碍（PTSD）的关联并没有因创伤经历类型的不同而有所不同，但在童年至青春期和成年早期中期比成年后期更强。童年时期的逆境与创伤后应激障碍（PTSD）的相关性存在差异，在儿童期、青春期和成年早期的关联性最强。各种创伤经历类型之间关联的一致性表明，童年时期的逆境与创伤经历后普遍易患 PTSD 的脆弱性有关。
Although childhood adversities are known to predict increased risk of post-traumatic stress disorder (PTSD) after traumatic experiences, it is unclear whether this association varies by childhood adversity or traumatic experience types or by age. To examine variation in associations of childhood adversities with PTSD according to childhood adversity types, traumatic experience types and life-course stage. Epidemiological data were analysed from the World Mental Health Surveys (n = 27 017). Four childhood adversities (physical and sexual abuse, neglect, parent psychopathology) were associated with similarly increased odds of PTSD following traumatic experiences (odds ratio (OR) = 1.8), whereas the other eight childhood adversities assessed did not predict PTSD. Childhood adversity-PTSD associations did not vary across traumatic experience types, but were stronger in childhood-adolescence and early-middle adulthood than later adulthood. Childhood adversities are differentially associated with PTSD, with the strongest associations in childhood–adolescence and early-middle adulthood. Consistency of associations across traumatic experience types suggests that childhood adversities are associated with generalised vulnerability to PTSD following traumatic experiences.
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影响因子：
2.8
作者：
Heleniak C;Jenness JL;Stoep AV;McCauley E;McLaughlin KA
通讯作者：
McLaughlin KA
影响因子：
--
作者：
KESSLER, RC;SONNEGA, A;NELSON, CB
通讯作者：
NELSON, CB
影响因子：
4.6
作者：
HENNESSY, KD;RABIDEAU, GJ;CUMMINGS, EM
通讯作者：
CUMMINGS, EM
影响因子：
--
作者：
Green, Jennifer Greif;McLaughlin, Katie A.;Berglund, Patricia A.;Gruber, Michael J.;Sampson, Nancy A.;Zaslavsky, Alan M.;Kessler, Ronald C.
通讯作者：
Kessler, Ronald C.
影响因子：
3.6
作者：
Espejo, Emmanuel P.;Hammen, Constance L.;Bor, William
通讯作者：
Bor, William