The impact of acquired brain damage in terms of epidemiology, economics and loss in quality of life.
The impact of acquired brain damage in terms of epidemiology, economics and loss in quality of life.
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DOI：
10.1186/1471-2377-11-46
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发表时间：
2011-04-18
期刊：
影响因子：
2.6
通讯作者：
Oliva-Moreno J
中科院分区：
文献类型：
--
作者：
Mar J;Arrospide A;Begiristain JM;Larrañaga I;Elosegui E;Oliva-Moreno J
获得性脑损伤（ABD）患者的脑部病变会中断身体，心理和社会领域的重要发展。中风和创伤性脑损伤（TBI）是两个主要原因。本研究的目的是估计2008年巴斯克地区和纳瓦拉人口中ABD的发病率和患病率，计算所需护理的相关成本，并最终评估健康相关生活质量的损失。一方面，进行了横断面调查，以估计ABD的发病率及其在成本和生活质量损失方面的后果，从诊断为中风和TBI的患者样本的演变。另一方面，建立了一个离散事件模拟模型，使ABD的患病率进行估计。最后，对巴斯克地区和纳瓦拉（2，750，000人）人口中ABD的正式和非正式成本进行了计算。横断面研究显示，脑卒中和TBI导致的ABD的发病率分别为61.8/10万/年和12.5/10万/年，而总患病率为657/10万人。SF-36躯体和精神成分评分分别为28.9和44.5。经计算，每年的总经济负担为3.8214亿欧元，分别占正式和非正式负担的215.27和166.87。每人每年的平均费用为21，040欧元。这项研究的主要结论是，ABD在流行病学和经济方面以及生活质量的损失方面都有很大的影响。获得的总体患病率相当于总人口的0.7%。巨大的经济负担几乎平均地分摊在正式和非正式费用之间。具体而言，人们发现，生活质量的物理方面受到的影响最严重。基于患病率的方法足以估计ABD的人口影响和补偿残疾所需的资源。
Patients with acquired brain damage (ABD) have suffered a brain lesion that interrupts vital development in the physical, psychological and social spheres. Stroke and traumatic brain injury (TBI) are the two main causes. The objectives of this study were to estimate the incidence and prevalence of ABD in the population of the Basque Country and Navarre in 2008, to calculate the associated cost of the care required and finally to assess the loss in health-related quality of life. On the one hand, a cross-sectional survey was carried out, in order to estimate the incidence of ABD and its consequences in terms of costs and loss in quality of life from the evolution of a sample of patients diagnosed with stroke and TBI. On the other hand, a discrete event simulation model was built that enabled the prevalence of ABD to be estimated. Finally, a calculation was made of the formal and informal costs of ABD in the population of the Basque Country and Navarre (2,750,000 people). The cross-sectional study showed that the incidences of ABD caused by stroke and TBI were 61.8 and 12.5 cases per 100,000 per year respectively, while the overall prevalence was 657 cases per 100,000 people. The SF-36 physical and mental component scores were 28.9 and 44.5 respectively. The total economic burden was calculated to be 382.14 million euro per year, distributed between 215.27 and 166.87 of formal and informal burden respectively. The average cost per individual was 21,040 € per year. The main conclusion of this study is that ABD has a high impact in both epidemiological and economic terms as well as loss in quality of life. The overall prevalence obtained is equivalent to 0.7% of the total population. The substantial economic burden is distributed nearly evenly between formal and informal costs. Specifically, it was found that the physical dimensions of quality of life are the most severely affected. The prevalence-based approach showed adequate to estimate the population impact of ABD and the resources needed to compensate the disability.
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影响因子：
1.2
作者：
Arrazola, A;Beguiristain, JM;Elizalde, B
通讯作者：
Elizalde, B
影响因子：
9.9
作者：
Lopez-Bastida, Julio;Serrano-Aguilar, Pedro;Oliva-Moreno, Juan
通讯作者：
Oliva-Moreno, Juan
影响因子：
168.9
作者：
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通讯作者：
Lopez, AD
影响因子：
2.5
作者：
Comas-Herrera, A;Wittenberg, R;Rothgang, H
通讯作者：
Rothgang, H
影响因子：
5.7
作者：
Mar, Javier;Sainz-Ezkerra, Maria;Moler-Cuiral, Jose Antonio
通讯作者：
Moler-Cuiral, Jose Antonio