Maternal salivary cortisol differs by fetal sex during the second half of pregnancy.

Maternal salivary cortisol differs by fetal sex during the second half of pregnancy.
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DOI:
10.1016/j.psyneuen.2010.09.005
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发表时间:
2011-05
影响因子:
3.7
通讯作者:
Laudenslager, Mark L.
Laudenslager, Mark L.
中科院分区:
医学2区
文献类型:
--
作者:
DiPietro, Janet A.;Costigan, Kathleen A.;Kivlighan, Katie T.;Chen, Ping;Laudenslager, Mark L.

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孕妇唾液皮质醇测定每周一次,从24至38周的妊娠。总样本包括120名妇女登记在交错的时间间隔,这样的方式,以产生每周的唾液皮质醇的措施,在怀孕的后半段。分层线性模型显示在此期间未结合的母体皮质醇的预期增加,在妊娠33周时增加率略有减速。与怀有女性胎儿的女性相比,怀有男性胎儿的女性最初的唾液皮质醇水平较高;在妊娠30周时,存在交叉,因此在怀有女性胎儿的女性中观察到较高的母体皮质醇。结果强调了考虑胎儿性别的重要性,作为一个调解人的同期和预测之间的关联,母体皮质醇和产前或产后的发展。
Maternal salivary cortisol was measured at weekly intervals from 24 to 38 weeks gestation. The total sample consisted of 120 women enrolled in staggered intervals in such a way as to generate weekly measures of salivary cortisol during the latter half of pregnancy. Hierarchical linear modeling revealed the expected increase in unbound maternal cortisol during this period, with a slight deceleration in rate of increase at 33 weeks gestation. Women carrying male fetuses had higher levels of salivary cortisol initially as compared to women carrying female fetuses; at 30 weeks gestation there was cross-over such that higher maternal cortisol was observed in women carrying female fetuses beyond this time and through term. Results highlight the importance of considering fetal sex as a moderator of contemporaneous and predictive associations between maternal cortisol and prenatal or postnatal development.
DOI: 10.1016/j.psyneuen.2008.06.008
发表时间: 2008-10
影响因子: 3.7
作者:
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通讯作者: Laudenslager, Mark L.
DOI: 10.1523/jneurosci.1424-08.2008
发表时间: 2008-09-03
期刊: The Journal of neuroscience : the official journal of the Society for Neuroscience
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