The epidemiology of psoriatic arthritis in Israel - a population-based study.

The epidemiology of psoriatic arthritis in Israel - a population-based study.
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DOI:
10.1186/s13075-017-1497-4
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发表时间:
2018-01-02
影响因子:
4.9
通讯作者:
Zisman D
Zisman D
中科院分区:
医学2区
文献类型:
--
作者:
Eder L;Cohen AD;Feldhamer I;Greenberg-Dotan S;Batat E;Zisman D

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关于银屑病关节炎(PsA)的流行病学信息有限,特别是在中东人群中。本研究的目的是估计以色列普通人群中PsA的患病率和发病率及其时间趋势。在这项研究中,从以色列最大的卫生基金Clalit Health Services (CHS)的数据库中提取了一组成年PsA患者,该数据库拥有超过440万名会员。计算2006 - 2015年普通人群PsA粗患病率和年龄、性别标准化患病率及发病率。评估了PsA患病率的变化与几个人口因素的关系。在2015年登记于CHS数据库的2,931,199名18岁及以上的个体中,4490名患者被诊断为PsA(322例事件),导致总体粗患病率和发病率分别为0.153% (95% CI 0.149%, 0.158%)和10.9 (95% CI 9.8, 12.3)每10万人。以色列报告的PsA患病率在2006年至2015年间翻了一番(从0.073%增至0.153%)。相比之下,全球发病率保持稳定,51岁至70岁人群的发病率逐渐增加。PsA与犹太民族、较高的社会经济地位和较高的体重指数有关。以色列PsA的患病率和发病率在南欧人群先前估计的范围内。在过去的十年中,在以色列的一般人群中观察到PsA患病率的增加。
There is limited information on the epidemiology of psoriatic arthritis (PsA) in general and in Middle Eastern populations in particular. The aims of this study were to estimate the prevalence and incidence rates of PsA and their temporal trends in the general population in Israel. In this study, a cohort of adult patients with PsA was derived from the database of Clalit Health Services (CHS), Israel’s largest health fund, with over 4.4 million members. The crude and age- and sex-standardized prevalence and incidence rates of PsA from 2006 to 2015 in the general population were calculated. The variation in PsA prevalence was assessed in relation to several demographic factors. Among the 2,931,199 individuals aged 18 years and older registered in the CHS database in 2015, 4490 patients had a diagnosis of PsA (322 incident cases), resulting in overall crude prevalence and incidence rates of 0.153% (95% CI 0.149%, 0.158%) and 10.9 (95% CI 9.8, 12.3) per 100,000 population, respectively. The reported prevalence of PsA in Israel has doubled between 2006 and 2015 (from 0.073% to 0.153%). In contrast, the global incidence rate remained stable, with a gradual increase in incidence among individuals aged 51 to 70 years. PsA is associated with Jewish ethnicity, high socioeconomic status, and higher body mass index. The prevalence and incidence of PsA in Israel are within the range of previous estimates from Southern European populations. An increase in the reported prevalence of PsA was observed over the past decade in the general population in Israel.
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