KaKs_Calculator 3.0: Calculating Selective Pressure on Coding and Non-coding Sequences.
KaKs_Calculator 3.0: Calculating Selective Pressure on Coding and Non-coding Sequences.
复制标题
KaKs_calculator 3.0:计算编码和非编码序列的选择压力
DOI:
10.1016/j.gpb.2021.12.002
复制
发表时间:
2022-06
影响因子:
9.5
通讯作者:
Zhang, Zhang
中科院分区:
文献类型:
--
作者:
Zhang, Zhang
KaKs_Calculator 3.0 is an updated toolkit that is capable of calculating selective pressure on both coding and non-coding sequences. Similar to the nonsynonymous/synonymous substitution rate ratio for coding sequences, selection on non-coding sequences can be quantified as the ratio of non-coding nucleotide substitution rate to synonymous substitution rate of adjacent coding sequences. As testified on empirical data, KaKs_Calculator 3.0 shows effectiveness to detect the strength and mode of selection operated on molecular sequences, accordingly demonstrating its great potential to achieve genome-wide scan of natural selection on diverse sequences and identification of potentially functional elements at a whole-genome scale. The package of KaKs_Calculator 3.0 is freely available for academic use only at https://ngdc.cncb.ac.cn/biocode/tools/BT000001.
登录
查看更多内容
DOI:
10.1038/nrc.2017.99
发表时间:
2018-01
期刊:
Nature reviews. Cancer
影响因子:
--
作者:
Anastasiadou E;Jacob LS;Slack FJ
通讯作者:
Slack FJ
影响因子:
11.4
作者:
Hurst, LD;Smith, NGC
通讯作者:
Smith, NGC
影响因子:
14.9
作者:
Liu L;Li Z;Liu C;Zou D;Li Q;Feng C;Jing W;Luo S;Zhang Z;Ma L
通讯作者:
Ma L
影响因子:
10.7
作者:
Katoh K;Standley DM
通讯作者:
Standley DM
影响因子:
14.9
作者:
Li, Wenjun;O'Neill, Kathleen R.;Thibaud-Nissen, Francoise
通讯作者:
Thibaud-Nissen, Francoise