LncRNAWiki 2.0: a knowledgebase of human long non-coding RNAs with enhanced curation model and database system.
LncRNAWiki 2.0: a knowledgebase of human long non-coding RNAs with enhanced curation model and database system.
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DOI:
10.1093/nar/gkab998
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发表时间:
2022-01-07
影响因子:
14.9
通讯作者:
Ma L
中科院分区:
文献类型:
--
作者:
Liu L;Li Z;Liu C;Zou D;Li Q;Feng C;Jing W;Luo S;Zhang Z;Ma L
LncRNAWiki, a knowledgebase of human long non-coding RNAs (lncRNAs), has been rapidly expanded by incorporating more experimentally validated lncRNAs. Since it was built based on MediaWiki as its database system, it fails to manage data in a structured way and is ineffective to support systematic exploration of lncRNAs. Here we present LncRNAWiki 2.0 (https://ngdc.cncb.ac.cn/lncrnawiki), which is significantly improved with enhanced database system and curation model. In LncRNAWiki 2.0, all contents are organized in a structured manner powered by MySQL/Java and curators are able to submit/edit annotations based on the curation model that includes a wider range of annotation items. Moreover, it is equipped with popular online tools to help users identify lncRNAs with potentially important functions, and provides more user-friendly web interfaces to facilitate data curation, retrieval and visualization. Consequently, LncRNAWiki 2.0 incorporates a total of 2512 lncRNAs and 106 242 associations for disease, function, drug, interacting partner, molecular signature, experimental sample, CRISPR design, etc., thus providing a comprehensive and up-to-date resource of functionally annotated lncRNAs in human.
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影响因子:
14.9
作者:
Li Z;Liu L;Jiang S;Li Q;Feng C;Du Q;Zou D;Xiao J;Zhang Z;Ma L
通讯作者:
Ma L
影响因子:
14.9
作者:
Gao Y;Shang S;Guo S;Li X;Zhou H;Liu H;Sun Y;Wang J;Wang P;Zhi H;Li X;Ning S;Zhang Y
通讯作者:
Zhang Y
影响因子:
14.9
作者:
BIG Data Center Members
通讯作者:
BIG Data Center Members
影响因子:
14.9
作者:
BIG Data Center Members
通讯作者:
BIG Data Center Members
影响因子:
14.9
作者:
Volders PJ;Verheggen K;Menschaert G;Vandepoele K;Martens L;Vandesompele J;Mestdagh P
通讯作者:
Mestdagh P