Distribution and evolution of the lectin family in soybean (Glycine max).

Distribution and evolution of the lectin family in soybean (Glycine max).
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DOI:
10.3390/molecules20022868
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发表时间:
2015-02-11
期刊:
Molecules (Basel, Switzerland)
影响因子:
--
通讯作者:
Van Damme EJ
Van Damme EJ
中科院分区:
其他
文献类型:
--
作者:
Van Holle S;Van Damme EJ

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凝集素是结合特定碳水化合物的一组不同的蛋白质,并在所有王国中发现。在植物中,凝集素参与了一系列重要的过程,如植物防御和胁迫信号。虽然大豆的基因组序列已经公布,但对大豆凝集素基因的丰度和扩增模式知之甚少。使用BLAST和隐马尔可夫模型,共359推定凝集素基因已被确定。此外,这些序列可以被归类到9个今天确定的12个植物凝集素家族。结构域组织的分析表明,大多数已鉴定的凝集素基因编码嵌合凝集素,由一个或多个凝集素结构域与其他已知的蛋白质结构域相结合。串联和节段重复事件都有助于凝集素基因家族的扩展。这些数据提供了一个详细的结构域的结构和分子进化的大豆凝集素基因家族的理解。
Lectins are a diverse group of proteins that bind specific carbohydrates and are found throughout all kingdoms. In plants, lectins are involved in a range of important processes such as plant defense and stress signaling. Although the genome sequence of Glycine max (soybean) has been published, little is known about the abundance and expansion patterns of lectin genes in soybean. Using BLAST and hidden Markov models, a total of 359 putative lectin genes have been identified. Furthermore, these sequences could be classified in nine of the twelve plant lectin families identified today. Analysis of the domain organization demonstrated that most of the identified lectin genes encode chimerolectins, consisting of one or multiple lectin domains combined with other known protein domains. Both tandem and segmental duplication events have contributed to the expansion of the lectin gene family. These data provide a detailed understanding of the domain architecture and molecular evolution of the lectin gene family in soybean.
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