The effects of fine particle components on respiratory hospital admissions in children.
The effects of fine particle components on respiratory hospital admissions in children.
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DOI：
10.1289/ehp.11848
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发表时间：
2009-03
影响因子：
10.4
通讯作者：
Marty M
中科院分区：
文献类型：
--
作者：
Ostro B;Roth L;Malig B;Marty M
流行病学研究表明，急性暴露于环境细颗粒物与死亡率和发病率之间存在关联。空气动力学直径< 2.5 μm的颗粒物（PM2.5）的特定化学成分对住院率的相对影响尚不清楚。本研究旨在估计暴露于PM2.5和几种污染物对因呼吸道疾病住院的儿童的风险。我们获得了2000年至2003年6个加州县< 19岁和< 5岁儿童因呼吸道疾病和包括肺炎、急性支气管炎和哮喘在内的几个亚类疾病而住院的每日计数数据，以及PM2.5及其成分（包括元素碳（EC）、有机碳（OC）和硝酸盐（NO3））的环境浓度。我们使用泊松回归来估计风险，同时控制重要的协变量。我们观察到PM2.5的几个成分与住院治疗的所有呼吸结果之间存在关联。例如，对于< 19岁儿童的总呼吸入院，PM2.5、EC、OC、NO3和硫酸盐滞后3天的四分位数范围与超额风险相关，分别为4.1%[95%置信区间（CI）， 1.8-6.4]、5.4% （95% CI, 0.8-10.3）、3.4% （95% CI, 1.1-5.7）、3.3% （95% CI, 1.1-5.5）和3.0% （95% CI, 0.4-5.7）。我们还观察到几种金属的关联。在凉爽的季节，还观察到与钾等其他几种物种的联系。PM2.5的成分与肺炎、支气管炎和哮喘等几种儿童呼吸道疾病的住院有关。由于暴露于成分（如EC、OC、NO3和K）及其相关来源，包括柴油和汽油废气、木材烟雾和其他燃烧源，在城市环境中无处不在，这可能是儿童住院的一个可识别和可预防的风险因素。
Epidemiologic studies have demonstrated an association between acute exposure to ambient fine particles and both mortality and morbidity. Less is known about the relative impacts of the specific chemical constituents of particulate matter < 2.5 μm in aerodynamic diameter (PM2.5) on hospital admissions. This study was designed to estimate the risks of exposure to PM2.5 and several species on hospital admissions for respiratory diseases among children. We obtained data on daily counts of hospitalizations for children < 19 and < 5 years of age for total respiratory diseases and several subcategories including pneumonia, acute bronchitis, and asthma for six California counties from 2000 through 2003, as well as ambient concentrations of PM2.5 and its constituents, including elemental carbon (EC), organic carbon (OC), and nitrates (NO3). We used Poisson regression to estimate risks while controlling for important covariates. We observed associations between several components of PM2.5 and hospitalization for all of the respiratory outcomes examined. For example, for total respiratory admissions for children < 19 years of age, the interquartile range for a 3-day lag of PM2.5, EC, OC, NO3, and sulfates was associated with an excess risk of 4.1% [95% confidence interval (CI), 1.8–6.4], 5.4% (95% CI, 0.8–10.3), 3.4% (95% CI, 1.1–5.7), 3.3% (95% CI, 1.1–5.5), and 3.0% (95% CI, 0.4–5.7), respectively. We also observed associations for several metals. Additional associations with several of the species, including potassium, were observed in the cool season. Components of PM2.5 were associated with hospitalization for several childhood respiratory diseases including pneumonia, bronchitis, and asthma. Because exposure to components (e.g., EC, OC, NO3, and K) and their related sources, including diesel and gasoline exhaust, wood smoke, and other combustion sources, are ubiquitous in the urban environment, it likely represents an identifiable and preventable risk factor for hospitalization for children.
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影响因子：
10.4
作者：
Hirshon JM;Shardell M;Alles S;Powell JL;Squibb K;Ondov J;Blaisdell CJ
通讯作者：
Blaisdell CJ
儿童早期下呼吸道疾病和空气污染。
影响因子：
10.4
作者：
Hertz-Picciotto, Irva;Baker, Rebecca James;Yap, Poh-Sin;Dostal, Miroslav;Joad, Jesse P;Lipsett, Michael;Greenfield, Teri;Herr, Caroline E W;Benes, Ivan;Shumway, Robert H;Pinkerton, Kent E;Sram, Radim
通讯作者：
Sram, Radim
DOI：
10.1097/ede.0b013e3181812bb7
发表时间：
2008-09
期刊：
Epidemiology (Cambridge, Mass.)
影响因子：
--
作者：
Franklin M;Koutrakis P;Schwartz P
通讯作者：
Schwartz P
影响因子：
2.1
作者：
Gottipolu, Reddy R.;Landa, Edward R.;Kodavanti, Urmila P.
通讯作者：
Kodavanti, Urmila P.
影响因子：
1.5
作者：
Kaewamatawong, Theerayuth;Shimada, Akinori;Takano, Hirohisa
通讯作者：
Takano, Hirohisa