Genetics, Development, and Evolution
Genetics, Development, and Evolution
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遗传学、发育和进化
DOI:
--
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发表时间:
1986
期刊:
影响因子:
--
通讯作者:
F. Ayala
中科院分区:
文献类型:
--
作者:
J. P. Gustafson;G. Stebbins;F. Ayala
Edward J. Klekowski, Jr., Hans Mohr,* and Nina Kazarinova-Fukshansky* Botany Department University of Massachusetts Amherst, MA 01003 U.S.A. *Biologisches Institut II Universitat Freiburg Schanzlestrasse 1 D-7800 Freiburg im Breisgau Federal Republic of Germany Since in plants Weismann's doctrine of the separation of soma and germ is invalid, somatic mutations may occur in cell lines which in turn give rise to meiocytes. Although some mutations are adaptive, the majority of mutations are disadvantageous and ultimately reduce the fitness of a ramet (or genet). Many anatomical and developmental characteristics may reduce the mutation frequency within ramets. Apical meristems may influence mutation frequency by either reducing the mutation rate or enhancing diplontic selection. The former is possible in meristems with permanent apical initials (structured meristems) through nonrandom DNA strand segregation and in meristems with impermanent apical initials (stochastic meristems) which have a meristeme d'attente. Diplontic selection is maximized in apical meristems in which the initials and derivative cells are least determined ontogenetically, thus allowing maximum intercellular competition (stochastic meristems). In spite of these mechanisms, the individual ramet meristems in long-lived genets still may be expected to diverge genetically through the fixation of mutations in the small cell pools within these meristems by mechanisms similar to Muller's Ratchet. The continued accumulation of disadvantageous mutations within
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DOI:
10.1073/pnas.77.10.6077
发表时间:
1980
影响因子:
11.1
作者:
Silver,LM;White,M;Artzt,K
通讯作者:
Artzt,K
影响因子:
2.7
作者:
Sternberg,PW;Horvitz,HR
通讯作者:
Horvitz,HR
DOI:
10.1073/pnas.81.21.6657
发表时间:
1984
影响因子:
11.1
作者:
Shimotohno,K;Wachsman,W;Takahashi,Y;Golde,DW;Miwa,M;Sugimura,T;Chen,IS
通讯作者:
Chen,IS
DOI:
10.1073/pnas.82.4.1002
发表时间:
1985
影响因子:
11.1
作者:
ElKareh,A;Murphy,AJ;Fichter,T;Efstratiadis,A;Silverstein,S
通讯作者:
Silverstein,S
影响因子:
2.9
作者:
Stanfield,SW;Lengyel,JA
通讯作者:
Lengyel,JA