Synthesis, performance, and application of molecularly imprinted membranes: A review

Synthesis, performance, and application of molecularly imprinted membranes: A review
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分子印迹膜的合成、性能和应用:综述

DOI:
10.1016/j.jece.2021.106352
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发表时间:
2021-12
影响因子:
7.7
通讯作者:
Ai-Ling Jia
Ai-Ling Jia
中科院分区:
工程技术2区
文献类型:
--
作者:
Hui Yang;Hong-Bo Liu;Zhi-Shu Tang;Zhi-Dong Qiu;Hua-Xu Zhu;Zhong-Xing Song;Ai-Ling Jia

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分子印迹膜(Molecularly Imprinted Membranes,MIMs)是膜分离技术(Membrane Separation Technology,MST)和分子印迹技术(Molecular Imprinting Technology,MIT)相结合的产物,它可以对模板分子进行分子记忆和识别,从而实现对模板分子的选择性识别、分离和检测。它们已经被研究了60多年,并且已经出现了大量的研究,但由于它们与新兴技术的兼容性,它们仍然是一个主要的研究焦点。近年来,MIM已广泛应用于传感器开发、手性分离、固相萃取、污水处理、食品科学、生物大分子合成、药物输送、草药化合物单体组分分离等领域。此外,一些研究人员将MIM与其他设备结合,以充分发挥其优势,如GC-MS,HPLC-MS,MS,搅拌棒,甚至智能手机。本文综述了金属离子膜的组成、合成、表征、性能和传质机理,并讨论了其在各个领域的应用。最后,简要评价了微机电系统在中医药领域应用的技术问题和发展趋势。
Molecularly imprinted membranes (MIMs), produced by the combination of membrane separation technology (MST) and molecular imprinting technologies (MIT), can perform molecular memory and recognition functions on template molecules, and then achieve selective recognition, separation, and detection. They have been studied for over 60 years and a large amount of research has emerged, but they remain a major research focus due to their compatibility with emerging technologies. Recently, MIMs have been widely used in sensor development, chiral separation, solid phase extraction, sewage treatment, food science, biomacromolecules synthesis, drug delivery, monomer component separation from herbal compounds, and more. Furthermore, some researchers have combined MIMs with other devices to give full play to its advantages, such as GC-MS, HPLC-MS, MS, stirring bar, and even smartphone. This review aims to summarize the composition, synthesis, characterization, performance, and mass transfer mechanisms of MIMs, and to discuss their application in various fields. Finally, the current technical issues and emerging trends of MIMs use in traditional Chinese Medicine are briefly evaluated.
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