Exacerbation of Chronic Obstructive Pulmonary Disease.

Exacerbation of Chronic Obstructive Pulmonary Disease.
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慢性阻塞性肺部疾病加剧。

DOI:
10.1007/s12013-015-0605-9
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发表时间:
2015-11
影响因子:
2.6
通讯作者:
Zhou X
Zhou X
中科院分区:
生物学4区
文献类型:
--
作者:
Zhou X;Li Q;Zhou X

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Chronic obstructive pulmonary disease (COPD) is a disease with high prevalence and substantial associated economical burden. A significant determinant of quality of life, long-term survival, and health care costs is an acute exacerbation of COPD. Acute exacerbations are provoked by respiratory viruses, altered airway microbiome, and environmental factors. The current treatment options are limited. In order to develop specific therapeutic measures, it is important to understand how acute exacerbations evolve. This review focuses on pathophysiology of stable and exacerbated COPD.
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