Analysing the detrimental effects of polyglutamine expansion

拟议的研究计划将为控制蛋白质聚集的过程及其与疾病的联系提供重要的基础见解。 研究蛋白质聚集的核心过程很重要，因为它将加深我们对蛋白质如何不适当地改变形状的理解以及我们对疾病过程的理解。 这些知识将提高澳大利亚的国际研究地位，并有可能产生新的治疗方法，防止神经变性。

The proposed research program, will provide significant fundamental insight into the processes that control protein aggregation and its link with disease. Investigating processes central to protein aggregation is important as it will deepen our understanding of how proteins inappropriately change shape and our understanding of disease processes. Such knowledge will increase Australia's international research standing, as well as having the potential to generate novel therapies, that prevent neurodegeneration.