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Determining genetic and non-genetic risk for schizophrenia in a high risk group

Determining genetic and non-genetic risk for schizophrenia in a high risk group
确定高危人群中精神分裂症的遗传和非遗传风险
批准号：
409453
负责人：
Bassett Anne S
金额：
$55.45万
依托单位：
Centre for Addiction and Mental Health (Toronto)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2019
资助国家：
加拿大
项目状态：
已结题
起止时间：
2019-09-01 至 2024-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=409453&lang=en
关键词：
22q11.2 Deletion Syndrome Bioinformatics Copy Number Variation Genetics Genomic Microdeletion Pathogenic Variants Penetrance Variable Expression Whole Genome Sequencing

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中文摘要
翻译
精神分裂症是一种严重的致残疾病，大约每100人中就有1人患病。这种脑部疾病经常影响年轻人，似乎在家庭中随机发生，病因尚不清楚。对于出生时带有基因缺失（缺失的DNA片段）的婴儿
英文摘要
Schizophrenia is a serious and disabling illness that affects about 1 in 100 people. The cause is unknown for this brain disease that often affects youths, seemingly at random in a family. For babies born with a genetic deletion (missing piece of DNA) on
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Outcomes and disease burden in a model of young adult multimorbidity
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Impact of tandem repeat expansions in schizophrenia
11th Biennial International 22q11.2 Conference
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