Acquisition of a Mass Spectrometer and Upgrading of FAB-MS Capabilities

质谱（MS）技术，如电子冲击（EI）和快速原子轰击（FAB）被用于探测内部结构细节，并获得大量有机、生物有机和有机金属分子的分子组成。获得能够执行这些最先进技术的仪器对于在几个化学领域进行前沿研究是必不可少的。化学共享仪器计划和生物仪器计划的支持将促进新型质谱仪的采购和FAB-MS能力的升级。将得到加强的主要研究领域包括：1)磷腈的化学性质2)大鼠α -1酸性糖蛋白的糖化位点分析3)翼素的化学性质4)毛细管区带电泳-质量分析光谱分析5)模板控制寡聚化6)合成有机金属化学

Mass spectral (MS) techniques such as Electron Impact (EI) and Fast Atom Bombardment (FAB) are used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic, bioorganic, and organometallic molecules. The acquisition of instrumentation capable of carrying out these state-of-the-art techniques is essential for the prosecution of frontier research in several fields of chemistry. The purchase of a new mass spectrometer and the upgrading of FAB-MS capabilities will be facilitated by support from the Chemistry Shared Instrumentation Program and the Biological Instrumentation Program. The major areas of research that will be enhanced include: 1) The chemistry of phosphazenes 2) Glycosation-site analysis of rat alpha-1 acid glycoprotein 3) Chemistry of pterins 4) Capillary zone electrophoresis-mass spectrometry 5) Template controlled oligomerizations 6) Synthetic organometallic chemistry