Acquisition of a Liquid Scintillation Counter

这是几个不同兴趣的研究人员为获得购买液体闪烁计数器的资金而提出的建议。该工具将用于支持五个主要项目。首先，在甲壳类动物生殖调节的研究中，将分离纯化刺激甲壳类动物卵巢组织活性的神经内分泌因子。其次，将研究几种淋巴瘤细胞系与纤维连接蛋白的相互作用，以帮助解释免疫反应的各个方面。第三，精氨酸激酶基因将作为真核生物（果蝇）中调控基因表达的模型进行研究。第四，最近在海洋无脊椎动物组织中发现的大量d -氨基酸（与通常出现的l -氨基酸相反）的意义将从功能和代谢的角度进行研究。最后，将调查葡萄球菌的抗生素耐药性，以确定耐药性是否与最近发现的青霉素结合蛋白有关。

This is a proposal from several investigators of diverse interests to obtain funds to purchase a liquid scintillation counter. The instrument will be used to support five main projects. First, neuroendocrine factors that stimulate the activity of crustacean ovarian tissue will be isolated and purified in studies of the regulation of crustacean reproduction. Second, the interaction of several lymphoma cell lines with fibronectin will be studied as a model to help explain aspects of the immune response. Third, the gene for arginine kinase will be studied as a model of regulated gene expression in a eukaryote (Drosophila). Fourth, the significance of the recent discovery of substantial amounts of D-amino acids (as opposed to the usually occurring L-amino acids) in marine invertebrate tissues will be investigated from the stand points of function and metabolism. Finally, antibiotic resistance in Staphylococcus will be investigated to determine if the resistance is related to a recently discovered penicillin-binding protein.