U.S.-Hungary Research on Comparative Neurobiology of Opioids

这项由纽约州立大学/老韦斯特伯里学院的乔治·斯特凡诺博士和匈牙利科学院/巴拉顿湖泊研究所的亚诺斯·萨兰基博士合作开展的美国-匈牙利合作研究项目的主要目标是研究简单生物体中阿片肽和阿片受体的基本神经生物学现象。共同努力将利用软体动物的无脊椎神经系统作为模型来阐明一般的阿片机制。该研究将提供更多关于进化原始和结构简单生物中阿片系统的信息，并为与脊椎动物的特征进行比较提供基础。研究结果将验证实验对象神经肽的结构随着时间的推移而保持不变的假设，只是有轻微的改变。该神经生物学项目通过使美国和东欧的专家在共同感兴趣和能力强的领域结合互补的人才和共享研究资源，实现了推进科学知识的计划目标。

The primary objective of this U.S.-Hungary cooperative research project between Dr. George Stefano of the State University of New York/College at Old Westbury and Dr. Janos Salanki of the Hungarian Academy of Sciences/Balaton Limnological Research Institute is to study basic neurobiological phenomena of opiate peptide and opiate receptor in simple organisms. Joint efforts will use well characterized invertebrate nervous systems of mollusks as models for elucidation of opioid mechanisms in general. The research should yield more information concerning opioid systems in evolutionary primitive and structurally simple organisms and provide a basis for comparison with vertibrate characteristics. Results will test the hypothesis that the structure of the subject neuropeptides has been conserved over time, with minor modifications. This project in neurobiology fulfills the program objective of advancing scientific knowledge by enabling experts in the United States and Eastern Europe to combine complementary talents and share research resources in areas of strong mutual interest and competence.