A Plant Science Center for the Experimental Analysis and Transfer of Plant Genes
A Plant Science Center for the Experimental Analysis and Transfer of Plant Genes
批准号:
8818551
负责人:
Maureen Hanson
金额:
$567.97万
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
1988
资助国家:
美国
项目状态:
已结题
起止时间:
1988-09-15 至 1995-07-31
中文摘要
莫琳·汉森博士和她在康奈尔大学的同事们将 建立植物科学中心。 该中心将提供 3名技术员的薪金和用品,最多12人 本科生暑期助教,最多12名高级研究生 学生(博士前研究员)和8名博士后 伙计们 大学将资助另外两个先进的 研究生研究员和多达10名研究生在他们的 前两年的学习。 适度的预算津贴将提供 用于改进输送DNA的设备(“粒子枪”) 包被在微粒体上的植物细胞核、线粒体和 叶绿体 这项技术被发明出来, 由康奈尔大学的生物学家合作开发, 农业和生命科学和工程师在康奈尔大学的国家 纳米纤维设施(现在是NSF资助的第11个年头)。 合作研究者和他们的博士后将进入新的 今年夏天,生物技术。 该设施,建在一个 康奈尔大学和纽约州分担了3200万美元的费用, 将有一个大的中央植物细胞培养和转化 设施(CCTF)。 它将主要为中心的 研究人员和他们的学生,但它将提供给 其他康奈尔大学的教师,为访问科学家,为科学家, 独立但位于校园内的博伊斯汤普森研究所, 植物研究和工业科学家。 除了培训计划和CCTF外,第三个 该中心的组成部分是技术开发项目。 它寻求分离重要植物基因的新方法, 植物基因功能及转基因实验分析 遗传信息进入细胞核和细胞器基因组。 中央 后者是生物弹道学--一个用来表示定向的 细胞外DNA或基因的递送,包被在 微粒,进入完整植物细胞的离散结构。 进一步开发这项新的但经过验证的技术至关重要 到高度可预测和高效的转化模型植物 系统和重要的农艺物种。 长期以来,康奈尔大学一直是学生和博士后的著名聚集地。 植物科学的学术和工业职业。 中心 将把不同的教师研究结合在一个核心主题中, 设想了多阶段的学生培训计划,并将房子 他们在一个最先进的设施,完全致力于 遗传学和发育科的教师,以及 生物化学、分子和细胞生物学。 除了有 校园合作研究者,强大的合作关系 与大学的农业实验站存在, 日内瓦,博伊斯汤普森研究所和美国农业部的植物基因 位于加州奥尔巴尼的表达实验室。 该中心的管理和行政将大大 在康奈尔大学成立五年的生物技术学院的帮助下, 该计划将在校园内提供服务, 对国家和工业成员的知名度和外联。 的 该计划是康奈尔大学,纽约州和 几家大公司。 第四个要素是来自 美国陆军将康奈尔大学命名为生物技术中心, 卓越 目前,在这些组成部分中, 主要强调植物科学,将提供由 中心
英文摘要
Dr. Maureen Hanson and her colleagues at Cornell University will establish a Plant Science Center. The Center will provide salaries and supplies for three technicians, for up to 12 undergraduate summer assistantships, up to 12 advanced graduate students (pre-doctorate fellows), and eight postdoctorate fellows. The University will fund an additional two advanced graduate fellows and up to 10 graduate students during their first two years of study. A modest budget allowance will provide for improvements in equipment ("particle gun") that delivers DNA coated on microprojectiles to plant cell nuclei, mitochondria and chloroplasts. This technology was invented, and is being developed cooperatively, by Cornell biologists in the College of Agriculture and Life Sciences and engineers at Cornell's National Nanofabrication Facility (now in its 11th year of NSF funding). Co-investigators and their postdocs will be moving into the new Biotechnology Building this summer. The facility, built at a cost of $32 million shared by Cornell and the State of New York, will have a large central plant Cell Culture and Transformation Facility (CCTF). It will operate chiefly for the Center's investigators and their students but it will be available for other Cornell faculty, for visiting scientists, for scientists of the independent but campus-housed Boyce Thompson Institute for Plant Research, and for industrial scientists. In addition to the training program and the CCTF, a third component of the Center is the technology development project. It seeks new means for isolating important plant genes, for the experimental analysis of plant gene function and for transferring genetic information into nuclear and organelle genomes. Central to the latter is biolistics--a term used to denote directed delivery of extracellular DNA or genes, coated on microprojectiles, into discrete structures of intact plant cells. Further development of this new but proven technology is crucial to highly predictable and efficient transformation of model plant systems and agronomically important species. Cornell has long been a notable preparer of students and postdocs for academic and industrial careers in plant science. The Center would unite diverse faculty research in a core theme with a well- conceived multiphasic student training program, and would house them in a state of the art facility dedicated entirely to the faculty in the Sections of Genetics and Development, and Biochemistry, Molecular and Cellular Biology. In addition to the on-campus co-investigators, strong collaborative relationships exist with the University's Agricultural Experiment Station at Geneva, The Boyce Thompson Institute and the USDA's Plant Gene Expression Laboratory at Albany, California. The Center's management and administration will be considerably aided by affiliation with Cornell's five-year old Biotechnology Program which will provide services on-campus as well as visibility and outreach to the State and industrial members. The Program is a consortium of Cornell, the State of New York and several large firms. A fourth element is support derived from the U.S. Army which has named Cornell a Biotechnology Center of Excellence. Presently, in none of these components is there a major emphasis on plant science which will be provided by the Center.
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