Presidential Young Investigator Award/Transmission of Stereochemical Information

美国加州大学圣地亚哥分校的Jay Siegel博士获得了有机和大分子化学项目的总统青年研究员奖。这项工作的重点是分子识别的广泛主题。分子识别是所有化学相互作用和反应的核心。它的细节不仅可以解释生物分子之间复杂的相互作用，还可以设计特定的催化过程和重要的新化学反应。将对单体和聚合物中的螺旋亚结构进行构象分析。这可能导致具有不同电子和显色性质的等构结构。这种结构在半导体、分子螺线管和非线性光学材料方面具有潜在的应用前景。此外，将制备有机金属芳烃-金属配合物，以研究芳烃中的金属配体动力学、金属中心反应性和键固定。

This Presidential Young Investigator Award given in the Organic and Macromolecular Chemistry Program provides support for the work of Dr. Jay Siegel, University of California, San Diego. This work is focused on the broad topic of molecular recognition. Molecular recognition is at the heart of all chemical interactions and reactions. Its details will explain not only the complicated interactions of biomolecules, but also will allow the design of specific catalytic processes and important new chemical reactions. Conformational analyses of helical substructures in both monomers and polymers will be undertaken. These may lead to isosteric structures having different electronic and chromophoric properties. Such structures have potential applications as semiconductors, molecular solenoids, and non-linear optical materials. In addition, organometallic arene-metal complexes will be prepared to study metal-ligand dynamics, metal-centered reactivity, and bond fixation in the arenes.