Role of astrocytes in blood-brain barrier regulation and CNS immunity
Role of astrocytes in blood-brain barrier regulation and CNS immunity
批准号:
179067
负责人:
Prat Alexandre
金额:
$51.82万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2009
资助国家:
加拿大
项目状态:
已结题
起止时间:
2009-03-01 至 2014-03-01
中文摘要
血脑屏障(BBB)限制有害分子和细胞从血液进入大脑。疾病中
与多发性硬化症(MS)一样,BBB不能阻止侵袭性白色血细胞(白细胞)进入大脑。这些
勒克
英文摘要
The Blood-Brain Barrier (BBB) restrict the passage of noxious molecules and cells from the blood to the brain. In diseases
like Multiple Sclerosis (MS), the BBB fails to prevent entry of aggressive white blood cells (leukocytes) into the brain. These
leuk
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Canada Research Chair - Tier 1
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批准号:471059
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项目类别:
-
资助金额:$101.99万
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财政年份:2022
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负责人:Prat Alexandre
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依托单位:
Integrin Alpha8 is a novel mediator of T lymphocyte migration across the CNS barriers
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批准号:401356
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项目类别:Operating Grants
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资助金额:$57.12万
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财政年份:2019
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负责人:Prat Alexandre
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依托单位:
A transgenic mouse model of multiple sclerosis offers new ways to identify mechanisms of progression and novel therapies
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批准号:357887
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项目类别:Operating Grants
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资助金额:$51.55万
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财政年份:2016
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负责人:Prat Alexandre
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依托单位:
Integrin alpha8 is a novel mediator of pro-inflammatory T lymphocyte migration across the CNS barriers
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批准号:366593
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项目类别:Operating Grants
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资助金额:$7.29万
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财政年份:2016
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负责人:Prat Alexandre
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依托单位:
The novel TH17-associated cytokine IL-26 mediates BBB breakdown and neuroinflammation
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批准号:303837
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项目类别:Operating Grants
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资助金额:$52.79万
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财政年份:2014
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负责人:Prat Alexandre
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依托单位:
Canada Research Chair Tier 1
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批准号:315442
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项目类别:
-
资助金额:$101.99万
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财政年份:2014
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负责人:Prat Alexandre
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依托单位:
Mechanisms of Lymphocytes Transmigration Across the Blood Brain Barrier
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批准号:313936
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项目类别:Operating Grants
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资助金额:$8.2万
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财政年份:2014
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负责人:Prat Alexandre
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依托单位:
Novel Adhesion Molecules Regulating CNS Inflammation
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批准号:279102
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项目类别:Operating Grants
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资助金额:$53.63万
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财政年份:2013
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负责人:Prat Alexandre
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依托单位:
Cytokines in Health and Diseases
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批准号:187029
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项目类别:Miscellaneous Programs
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资助金额:$0.51万
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财政年份:2009
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负责人:Prat Alexandre
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依托单位:
海外基金