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Role of astrocytes in blood-brain barrier regulation and CNS immunity

Role of astrocytes in blood-brain barrier regulation and CNS immunity
星形胶质细胞在血脑屏障调节和中枢神经系统免疫中的作用
批准号:
179067
负责人:
Prat Alexandre
金额:
$51.82万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2009
资助国家:
加拿大
项目状态:
已结题
起止时间:
2009-03-01 至 2014-03-01

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中文摘要
翻译
血脑屏障(BBB)限制有害分子和细胞从血液进入大脑。疾病中 与多发性硬化症(MS)一样,BBB不能阻止侵袭性白色血细胞(白细胞)进入大脑。这些 勒克
英文摘要
The Blood-Brain Barrier (BBB) restrict the passage of noxious molecules and cells from the blood to the brain. In diseases like Multiple Sclerosis (MS), the BBB fails to prevent entry of aggressive white blood cells (leukocytes) into the brain. These leuk
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会议论文
Canada Research Chair - Tier 1
  • 批准号:
    471059
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2022
  • 负责人:
    Prat Alexandre
  • 依托单位:
Integrin Alpha8 is a novel mediator of T lymphocyte migration across the CNS barriers
A transgenic mouse model of multiple sclerosis offers new ways to identify mechanisms of progression and novel therapies
Integrin alpha8 is a novel mediator of pro-inflammatory T lymphocyte migration across the CNS barriers
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