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Uncovering the Oncogenic Drivers of Cancer Glycocalyx Remodelling Using Chemical-Genetic Screening

Uncovering the Oncogenic Drivers of Cancer Glycocalyx Remodelling Using Chemical-Genetic Screening
使用化学遗传筛选揭示癌症糖萼重塑的致癌驱动因素
批准号:
373733
负责人:
Wisnovsky Simon
金额:
$10.2万
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-09-01 至 2019-09-01

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中文摘要
翻译
癌细胞的表面经常被糖分子包裹,这有助于它们逃避免疫系统的检测。这项研究的目的是发现目前尚未表征的癌细胞内产生这种修饰的遗传变化
英文摘要
The surfaces of cancer cells are frequently coated with sugar molecules that help them to evade detection by the immune system. This research aims to discover the currently uncharacterized genetic changes within cancer cells that produce this modification
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海外基金