The Ultracentrifuge as a Tool in Studies of Cell Function

正在开发一系列实验室练习， 学生对细胞功能的理解。这些补体 以前存在的细胞结构练习。分离和 纯化细胞成分，一个超级离心器和转子正在被 购买。仪器Beckman TL-100，具有小样本 体积和高离心力，以实现快速和精确 分离细胞成分，使纯样品可用 在实验室期限内进行研究。这使得 学生们可以探索分子机制， 通过实验纯化的成分， 比通过低速离心获得的粗级分高。的 建议的练习将帮助学生理解我们是如何 来理解细胞之间复杂的相互作用 流程. 学院将提供相当于 奖

A series of lab exercises are being developed that will enhance the students' understanding of cell function. These complement previously existing exercises on cell structure. To isolate and purify cell components, an ultracentrifuge and rotors are being purchased. The instrument, the Beckman TL-100, has small sample volumes and high centrifugal forces to effect rapid and exact separations of cell constituents, making pure samples available for study within the time limit of a laboratory period. This makes it possible for the students to explore the molecular mechanisms of cell function by experimenting with purified components rather than crude fractions obtained by lower-speed centrifugations. The proposed exercises will help students understand how we have come to understand the complex interactions that coordinate cell processes. The college will contribute an amount equal to the award.