Iron Uptake in Arabidopsis Thaliana

这是一项职业发展奖，旨在支持Guerinot博士提出的利用生化、遗传和分子遗传方法研究模式高等植物拟南芥的铁摄取。Guerinot博士对铁代谢有着长期的兴趣，到目前为止，他一直专注于慢生根瘤菌/大豆共生中的铁摄取和代谢，特别强调细菌伴侣的铁摄取和铁应激生理。她想扩大她的研究，以铁的吸收和代谢的植物伙伴的调查。为了促进这些研究，她建议将拟南芥作为一个模型系统，并最终将通过这些研究获得的知识转移到大豆的研究中。预计这一新的研究路线将大大提高圭里诺博士的职业生涯。

This is a Career Advancement Award to support Dr. Guerinot's proposed research on iron uptake in the model higher plant, Arabidopsis thaliana, using biochemical, genetic, and molecular genetic approaches. Dr. Guerinot has long-standing interest in iron metabolism, and has until now focussed on iron uptake and metabolism in the Bradyrhizobium/soybean symbiosis, with particular emphasis on iron uptake and iron-stress physiology in the bacterial partner. She would like to expand her research to investigations of iron uptake and metabolism in the plant partner. To facilitate these studies, she has proposed to work on Arabidopsis as a model system, with the intention of ultimately transferring knowledge gained through these studies to studies of the soybean. It is anticipated that this new line of research will significantly enhance Dr. Guerinot's career.