Paired Electrochemical Synthesis of Organic Compounds

第一阶段小企业创新研究（SBIR） 是给 研究开发商业上可行的方法， 从玉米糖或原料中获得的蔗糖的转化 手杖 或甜菜糖转化为可用的化学原料。 的 目标是 为了建造和测试一个电化学反应器， 电化学合成山梨糖醇和葡萄糖酸 水性 在环境温度下操作的葡萄糖（谷物糖浆）溶液 温度和压力。 第一阶段的具体目标将 是： (1)质子交换膜的设计与制备 （PEM）- 基于单电池的电化学反应器， 电极 表面积与反应物溶液体积之比， 的 在100 ℃以下的温度下操作;（2）进行 基本 调查和评价单一 细胞 基于质子交换膜的电化学反应器， 葡萄糖转化为山梨糖醇和葡萄糖酸 阴极和阳极，分别;和（3）识别 技术和建立程序， 有机化合物的鉴定和定量 上产生 以这种方式电化学处理葡萄糖溶液。 将测试各种阴极/阳极材料以查看它们是否 是 选择性地从葡萄糖形成山梨糖醇和葡萄糖酸 而 同时降低了所需的电能， 实现 反应速度快。 拟议技术方案的预期成果 方法是：（1）获得经济效益的清洁技术 好处 从多种糖化合物己糖和戊糖 （木糖） 木糖醇和木糖酸）;（2）无污染，高效 能够成对电化学合成糖的方法 醇和酸;和（3）电化学过程 操作 在温和的条件下， 化学 原料。

This Phase I Small Business Innovation Research (SBIR) grant is for research on developing a commercially viable method for the conversion of sucrose, obtained either from corn sugar or raw cane or beet sugar, into a usable chemical feedstock. The objective is to build and test an electrochemical reactor for the paired electrochemical synthesis of sorbitol and gluconic acid in aqueous solutions from glucose (grain syrup) operated at ambient temperature and pressure. Specific objectives of Phase I will be: (1) the design and fabrication of a proton exchange membrane (PEM)- based single cell electrochemical reactor that maximizes electrode surface area-to-reactant solution volume and that is capable of operating at temperatures up to 100oC; (2) carrying out fundamental investigations and evaluation of the performance of a single cell PEM-based electrochemical reactor for the simultaneous transformation of glucose to sorbitol and gluconic acid at the cathode and anode, respectively; and (3) identification of techniques and the establishment of procedures for the identification and quantification of organic compounds produced on electrochemical treatment of glucose solutions in this manner. Various cathode/anode materials will be tested to see if they are selective in forming sorbitol and gluconic acid from glucose while at the same time lowering the electrical energy needed to achieve fast reaction rates. The anticipated results arising from the proposed technical approach are: (1) a clean technology for deriving economic benefits from a variety of sugar compounds both hexoses and pentoses (xylose to xylitol and xylonic acid); (2) a non-polluting, efficient process, capable of paired electrochemical synthesis of sugar alcohols and acids; and (3) an electrochemical process operating under mild conditions that yields pharmaceutical-grade chemical feedstocks.