Neurochemical predictors of cognition and the impact of brain stimulation

该项目旨在确定整个大脑中兴奋和抑制之间的神经化学平衡（E/I平衡）如何与执行功能相关，以及这种平衡如何受到非侵入性脑刺激的影响。脑刺激在应用环境中显示出增强执行功能的巨大希望，但其神经化学基础尚不清楚。利用先进的成像和增产技术，该项目旨在全面了解增产、E/I平衡和执行功能之间的因果关系。结果和益处包括确定决定刺激效果的神经化学特征，并为应用方案的设计提供信息。

This project aims to determine how neurochemical equilibrium between excitation and inhibition (E/I balance), across the brain, is associated with executive function and how this balance is influenced by non-invasive brain stimulation. Brain stimulation shows immense promise for enhancing executive function in applied settings, but the neurochemical basis for this is unknown. Using advanced imaging and stimulation techniques, the project aims to provide comprehensive insights into the causal relationship between stimulation, E/I balance and executive function. Outcomes and benefits include identifying neurochemical characteristics that determine stimulation efficacy and informing the design of protocols for applied use.