Chemistry of Iridium Hydride Complexes Synthesized by Addition of Non-Metal Hydrides

这个无机、生物无机和有机金属化学项目的奖项支持弗吉尼亚理工学院化学系的Joseph S. Merola博士对各种有机底物与磷化氢铱络合物的氧化加成反应的研究。底物包含E-H键，其中E = H，B，C，N，O。将研究由此产生的一系列E-Ir- h化合物的反应化学，特别是关于在E-Ir和H-Ir键中插入不饱和分子的反应化学。因此，在化学中发生在金属中心的与氢化、催化硼氢化、C-H键活化、氢胺化和氢烷醇化有关的基本过程将被研究。为了提高这些体系的催化活性，铱上的阴离子基团会发生变化。有些反应将在水溶液中进行。氧化加成反应在有机金属化合物的催化化学和化学计量化学中都起着重要的作用。该项目的长期目标是开发用于向不饱和有机化合物添加E-H键的催化剂体系。这可能具有重要的工业意义，但由于这些潜在重要过程的反应化学尚不为人所知，因此也有望取得根本性的进展。

This award in the Inorganic, Bioinorganic, and Organometallic Chemistry Program supports research by Dr. Joseph S. Merola of the Chemistry Department, Virginia Polytechnic Institute, on oxidation addition reactions of various organic substrates to iridium phosphine complexes. The substrates involve E-H bonds, where E = H,B,C,N,O. The reaction chemistry of the series of E-Ir-H compounds thus generated will be investigated, especially with respect to the insertion of unsaturated molecules into the E-Ir and H-Ir bonds. Thus, fundamental processes occurring at the metal center in chemistry related to hydrogenation, catalytic hydroboration, C-H bond activation, hydroamination, and hydroalkoxlylation will be studied. Anionic groups on the iridium will be varied in order to promote the catalytic activity of these systems. Some of the reactions will be carried out in aqueous solution. %%% Oxidation addition reactions play an important role in both catalytic and stoichiometric reaction chemistry of organometallic compounds. The long range goal of this project is to develop catalyst systems for the addition of E-H bonds to unsaturated organic compounds. This could have important industrial implications but since the reaction chemistry of these potentially significant processes is not well known, fundamental advances are also anticipated.