U.S. Russia Joint Collaborative Research: Y Chromosome Variation in Native Human Populations of Siberia

拔出锤-9423429 将现代人的起源与非洲联系起来的广为人知的遗传学研究主要基于母系遗传的线粒体DNA，这并没有揭示男性在人类迁移动态中的作用。这一研究项目的总体目标是利用Y染色体（仅由男性携带）作为一种独立的工具，检验关于现代人口的起源和迁移模式以及世界某些地区男性专用基因流动的假设。这项研究是第一次系统地研究人类Y染色体遗传变异的全面努力。这些父系来源的数据将补充北方欧亚大陆日益丰富的语言学和考古学数据，并对人类进入新大陆的起源和迁移模式提供更完整的看法。 *** ??

ABSTRACT HAMMER OPP-9423429 Well publicized genetic studies linking the origin of modern humans to Africa have been based largely on maternally-inherited mitochondrial DNA, which reveal nothing about the role of males in the dynamics of human migration. The overall goal of this research project is to use the Y chromosome (carried by males alone) as an independent tool to test hypotheses regarding the origin and migration patterns of modern human populations and the male-dedicated gene flow in selected regions of the world. This research is the first comprehensive effort to systematically examine genetic variation in the human Y chromosome. These paternally derived data will complement the growing wealth of linguistic and archaeological data in northern Eurasia and give a more complete view of the origins and migration patterns of humans into the New World. *** ??