SBIR Phase II: Development of a Bioremediation System for the Degradation of Ozone-Depleting Substances

Deflaun 9423987这个小企业创新研究第二阶段项目涉及开发一种基于生物催化剂的反应器系统，用于销毁已知会导致臭氧消耗和全球变暖的氢卤烃化合物。 在第一阶段的工作中，母牛分枝杆菌JOB 5被选为唯一适合用于生物滴滤器，旨在处理空气排放。 第二阶段的研究将试图：（1）建立潜在的共底物的氢卤烃氧化;（2）开发一个在线的气相色谱方法，用于连续监测污染物卤代烃;（3）表明使用M。 实验室规模的生物滴滤器中的caccae JOB 5，并验证目标化合物的矿化;（4）建立这些生物过滤装置的最佳进料速率;（5）获得生物滴滤器长期使用的数据;（6）在建造全尺寸生物滴滤塔的估算的成本分析中使用该信息，以及与传统物理/化学处理技术相比，预测资本和运营成本;以及（7）将这些信息纳入该技术的最终报告和商业化计划。 有人建议，一个生物反应器系统的去除和销毁的氢卤烃蒸气排放的发展可能会提供显着的成本降低和整体节省相比，今天的传统的空气处理选项。 这个小型企业创新研究第二阶段项目涉及开发一种基于生物催化剂的反应器系统，用于破坏导致臭氧消耗和全球变暖的污染物化合物。 在第一阶段的工作中，母牛分枝杆菌JOB 5被选为最适合用于生物滴滤器，旨在从空气中去除这些污染物。 第二阶段的研究将试图：（1）找出什么样的化合物可以从空气中去除这种微生物为基础的过滤系统;（2）开发一种在线气相色谱法，连续测量这些污染物在空气中的浓度;（3）显示使用M.实验室规模的生物滴滤器中的木薯JOB 5，并验证过滤装置破坏目标化合物;（4）确定过滤系统可以破坏污染物的速率;（5）获得生物滴滤器长期使用的数据;以及（6）在建造全尺寸生物滴滤器的成本分析中使用该信息，以及将这种新型生物技术的资本投资和运行成本与常规物理/化学处理技术进行比较。 最后，这些数据将被纳入这项新技术的最终报告和商业化计划中。 有人建议，生物反应器系统的发展可以提供显着的成本降低和整体节省相比，今天的传统的空气处理方案。 ***

Deflaun 9423987 This Small Business Innovation Research Phase II project involves the development of a biocatalyst-based reactor system for the destruction of hydrohalocarbon compounds known to contribute to ozone depletion and global warming. During Phase I work, Mycobacterium vaccae JOB5 was selected as uniquely suited for use in biotrickling filters designed to treat air emission. Phase II research will attempt to: (1) establish potential co-substrates for hydrohalocarbon oxidation; (2) develop an on-line gas chromatographic method for continuous monitoring of pollutant halogenated hydrocarbons; (3) show the feasibility of using M. caccae JOB5 in bench-scale biotrickling filters and verify mineralization of target compounds; (4) establish the optimal feeding rate to these biofiltering devices; (5) obtain data on the long-term use of the biotrickling filter; (6) use this information in cost analyses of estimates for construction of a full-scale biotrickling filter, and in projecting capital and operating costs in comparison with those of conventional physical/chemical treatment technologies; and (7) incorporate this information into a final report and commercialization plan for the technology. It is suggested that the development of a bioreactor system for the removal and destruction of hydrohalocarbon vapor emissions potentially could offer significant cost reductions and overall savings compared to today's conventional air treatment options. %%% This Small Business Innovation Research Phase II project involves the development of a biocatalyst-based reactor system for the destruction of pollutant compounds that contribute to ozone depletion and global warming. During Phase I work, Mycobacterium vaccae JOB5 was selected as best suited for use in biotrickling filters designed to remove these pollutants from the air. Phase II research will attempt to: (1) find out what kind of compounds can be removed from air with this microbe-based filter system; (2) deve lop an on-line gas chromatographic method to continuously measure the concentration of these pollutants in air; (3) show the feasibility of using M. caccae JOB5 in bench-scale biotrickling filters and verify that the filtering device destroys the target compounds; (4) establish the rate at which the filter system can destroy pollutants; (5) obtain data on the long-term use of the biotrickling filter; and (6) use this information in cost analyses for building a full-scale biotrickling filter, and comparing capital investments and operating costs for this novel biotechnology with conventional physical/chemical treatment technologies. Finally, these data will be incorporated into a final report and commercialization plan for this novel technology. It is suggested that the development of a bioreactor system could provide significant cost reductions and overall savings compared to today's conventional air treatment options. ***