Antibodies as Tools in Cell Biology

生物系正在实施一项修订后的课程，强调通过调查实验室的科学过程。 学生开始他们的生物学研究与课程的结构和功能的生物体和进化和生态学在第一年。 在第二年，学生参加分子遗传学和细胞生物学课程。 后一门课程强调蛋白质在细胞中的作用，是课程改进的主要目标之一。 一门细胞生物学的现代课程正在通过强调如何研究细胞来教授。 学生谁已经学会了许多应用技术在分子遗传学研究细胞从他们以前的课程，现在可以参加一个新的部分抗体作为工具，在细胞生物学的新课程。 对于这个项目，低温恒温器可以快速方便地制备冷冻切片，并保留各种标本中蛋白质的抗原性。 然后用市售抗体对这些冷冻切片进行染色，与使用石蜡包埋材料的旧方法相比，成功的可能性更大。 使用抗体作为研究蛋白质分布的工具也是发育生物学高级课程实验室的主要部分，少数民族高中生的暑期课程，以及生物学和心理学系的研究项目。 除了使用这种现代化的仪器，结果的沟通，以其他学生将被强调。 为了强调这一点，并提高学生在光学显微镜的培训，一个研究质量的教学显微镜配备荧光显微镜，显微摄影和视频成像也正在购买。 这种显微镜使学生群体可以一起查看他们的结果，而不是孤立的。 这种新的显微镜还允许学生永久记录他们的结果，以供以后分析。

The Department of Biology is implementing a revised curriculum that emphasizes the process of science through investigative laboratories. Students begin their study of biology with courses in Structure and Function of Organisms and Evolution and Ecology in the first year. In the second year, students take courses in Molecular Genetics and The Biology of Cells. The latter course, which will emphasize the roles of proteins in cells, is one of the primary targets of curricular improvements. A modern course in cell biology is being taught by emphasizing how cells are studied. Students who have learned many applications of techniques in molecular genetics to study cells from their prior coursework can now attend a new section on antibodies as tools in cell biology in the new course. For this project, a cryostat prepares frozen sections quickly and easily and preserves the antigenicity of proteins from various specimens. These frozen sections are then stained with commercially available antibodies with a greater likelihood of success than the old method of using paraffin-embedded material. Use of antibodies as tools to study protein distribution is also a major part of the laboratories in an upper-level course in developmental biology, a summer program for minority high school students, and research projects in both the biology and psychology departments. In addition the use of this modern instrumentation, communication of results to other students will be emphasized. For this emphasis and for improvment of students' training in light microscopy, a research-quality teaching microscope equipped for fluorescence microscopy, photomicroscopy, and video imaging is also being purchased. This microscope makes it possible for groups of students to view their results together instead of in isolation. This new microscope also allows students to have a permanent record of their results for later analysis.