Intelligent Tutor for Concepts in Molecular Genetics

Shiladitya DasSarma将于1995财年购买9551531 U马萨诸塞州阿默斯特，售价273,459美元，MA 1003 ILI-实验室发展的领导力：生命科学标题：分子遗传学概念的智能导师这个项目正在开发一个计算机实验室，为本科生辅导分子遗传学的基本概念。涵盖的主题包括(A)DNA结构和复制，(B)RNA转录、翻译和剪接，(C)基因重组、修复和转座，(D)基因工程和重组DNA技术，以及(E)现代基因组分析和社会影响。向本科生教授这些基本的遗传学概念的主要挑战是(1)传递动态分子过程的视觉图像，(2)提供一个坚实的智力框架来探索遗传过程之间的相互关系，以及(3)在更高级的水平上，传达遗传学原理进化的实验基础。该项目利用计算机硬件(增加的存储器大小和数据存储)和软件(智能教学系统)的最新进展来开发一个多媒体教学包，它以比目前通过讲座或教科书可能的方式更深入和更有效地传达分子遗传学的视觉图像、概念关系和实验基础。这款名为“MOLGENT”的电子导师正在其开发阶段接受测试，包括生物学、微生物学、分子和细胞生物学入门课程，以及马萨诸塞大学阿默斯特分校一门名为“分子遗传学概念”的创新高级课程。通过学生讨论小组对教程的有效性进行监控和改进。一旦开发完成，原型软件将通过在生物学会(如美国微生物学会、美国遗传学会和美国生物化学和分子生物学学会)会议的教育部分进行演示来推广，并通过出版商广泛分发。

Shiladitya DasSarma DUE 9551531 U of Massachusetts Amherst FY1995 $273,459 Amherst, MA 1003 ILI - Leadership in Laboratory Development: Life Sciences Title: Intelligent Tutor for Concepts in Molecular Genetics This project is developing a computer laboratory fop tutoring undergraduate students in fundamental concepts of molecular genetics. The topics covered include (a) DNA structure and replication, (b) RNA transcription, translation, and splicing, (c) genetic recombination, repair, and transposition, (d) genetic engineering and recombinant DNA technology, and (e) modern genomic analysis and societal implications. The major challenges in teaching these fundamental genetic concepts to undergraduates are (1) transmitting the visual imagery of dynamic molecular processes, (2) providing a solid intellectual framework to explore interrelationships between genetic processes, and (3) at more advanced levels, conveying the experimental basis for evolution of genetic principles. The project exploits recent advances in computer hardware (increased memory size and data storage) and software (intelligent tutoring systems) to develop a multimedia tutorial package which conveys the visual imagery, conceptual relationships, and experimental basis of molecular genetics in a deeper and more effective manner than currently possible through lectures or textbooks. The electronic tutor, named "MOLGENT", is being tested during its developmental phase, in a variety of undergraduate classes, including introductory biology, microbiology, and molecular and cellular biology courses, and an innovative senior-level course entitled "Concepts in Molecular Genetics" at the University of Massachusetts at Amherst. The effectiveness of tutorials is being monitored and improved through student discuss ion groups. Once developed, the prototype software will be promoted via demonstrations at the educational section of meetings of biological societies (e.g. American Society for Microbiology, Genetics Society of America, and American Society for Biochemistry and Molecular Biology) and distributed broadly via publishers.