Renovation of Unusable Laboratories into a Modern Pharmaceutical Engineering Research Facility

1995年9月，罗格斯大学化学和生化工程系创建了制药工程专业，这是美国第一个此类专业。该计划的设立是为了通过系统地应用工程概念来产生制造和加工材料所需的各种技术来提高药品制造过程的性能。在某些情况下，所产生的制造程序在工艺条件或原材料性质的变化方面非常不稳定，从而损害了生产过程的有效性。工程概念，如质量，动量和能量平衡，热力学，传输现象，胶体和表面化学，被用来描述过程中的基本操作。产生先进技术，以提高制造过程的可预测性、可靠性和可控性，是该计划的重要目标之一。目前，该项目的研究活动在分散在校园内的五座不同建筑中进行。这种地理上的分散使得很难实现凝聚力和发展有效的协作。此外，可用的实验室空间不太适合进行许多必要的研究调查。该合同将部分支持布希校区工程综合体C号楼的翻新工程。最初建于1963年，现有的结构自那时以来就没有翻新过，实验室处于恶化的高级状态。该项目将通过安装通风柜、适当通风的空气处理设备、新的电力和管道服务以及重新配置实验室来纠正干扰研究进行的缺陷。目标空间将被改造成由五个实验室和六个辅助仪表室组成的现代粉末技术研究设施，为巩固方案的所有实验活动提供足够的空间。在该项目的推动下，研究能力的提高和强有力的合作将加速和成倍地开发新技术，增强制造过程的可预测性和可控性。由于美国严重缺乏受过粉末技术培训的研究人员，该项目将对该部开展研究培训活动的能力产生重大影响，确保在这一多学科研究领域接触到代表性不足的群体。预计一旦该项目完全建立，其他学术机构将有兴趣开发类似的项目，以满足对美国经济至关重要的行业的需求。

In September 1995, Rutgers University's Department of Chemical and Biochemical Engineering created the Pharmaceutical Engineering Program, the first one of its kind in the United States. The Program was established to improve the performance of the pharmaceutical manufacturing process by systematically applying engineering concepts to generate a wide array of technologies needed for the making and processing of materials. In some instances, the resulting manufacturing procedures are highly unstable with respect to changes in processing conditions or in raw materials properties, that the validity of the production process is compromised. Engineering concepts such as mass, momentum and energy balances, thermodynamics, transport phenomena, colloidal and surface chemistry, are used to characterize basic operations in the process. Generating advanced technologies, for improving the predictability, reliability, and controllability of the manufacturing process, is one of the important objectives of the program. Currently, research activities of the program are conducted in five different buildings scattered across campus. This geographic dispersion makes it difficult to achieve cohesiveness and develop effective collaborations. Moreover, available laboratory space is poorly suited to perform many of the necessary research investigations. This award will partially support the renovation of Building C of the Engineering Complex on the Busch Campus. Originally built in 1963, the existing structure has not been renovated since that time and laboratories are in an advanced state of deterioration. This project will correct deficiencies interfering with the conduction of research by installing fume hoods, air handling equipment for proper ventilation, new electrical and plumbing services, and reconfiguring laboratories. Targeted space will be renovated into a modern powder technology research facility consisting of five laboratories and six auxiliary instrument rooms, providing sufficient space to consolidate all of the Program's experimental activities. Improved research capabilities and strong collaborations, facilitated by the project, will accelerate and multiply the development of new technologies, enhancing the predictability and controllability of the manufacturing process. Because the US suffers from an acute shortage of researchers trained in powder technology, the project will have a major impact on the Department's ability to develop research training activities, ensuring access to underrepresented groups in this multidisciplinary area of study. It is anticipated that once the Program is fully established, other academic institutions will be interested in developing similar programs addressing the needs of an industry critical to the US economy.