Comprehensive Upgrade of a Shared Campus NMR Facility

该提案要求提供资金，用于升级加州大学戴维斯分校共享校园NMR设施的四台光谱仪。升级将包括更换当前光谱仪的控制台、探头、探头接口和梯度（如果存在），仅保留磁铁。升级后的系统将包括四个用于核磁共振光谱和核磁共振成像（MRI）的最先进的光谱仪：窄孔垂直磁体500 MHz，宽孔垂直400 MHz，宽孔垂直300 MHz和水平孔（183 mm）300 MHz。这些仪器将用于化学、生物学、材料科学和工程领域的各种研究。NMR设施仪器每年由来自戴维斯校区22个部门的40多名教职员工使用，每年直接费用为3，239，000美元，全部或部分用于NMR研究，包括9项NSF赠款。该提案描述了该设施19个最密集的主要用户的研究计划，记录了现有设备的不足之处，并详细说明了新仪器将带来的好处。本文所示的仪器是必不可少的主要用户的研究计划，也将发挥重要作用，在戴维斯校园的教育和专业培训。

This proposal requests funding to upgrade four spectrometers of the shared campus NMR Facility at the University of California, Davis. The upgrades will consist of replacing the console, shims, probes, probe interface, and gradients (when present) of the current spectrometers, retaining only the magnets. The upgraded systems will constitute four state-of-the-art spectrometers for NMR spectroscopy and NMR imaging (MRI): a narrow bore vertical magnet 500 MHz, a wide bore vertical 400 MHz, a wide bore vertical 300 MHz, and a horizontal bore (183 mm) 300 MHz. The instruments will be used for a wide variety of studies in the fields of chemistry, biology, materials science, and engineering. The NMR Facility instrumentation is utilized annually by over 40 faculty members from 22 departments of the Davis campus with $3,239,000 in annual direct costs of extramural funding directed wholly or in part to NMR research, including nine NSF grants. This proposal describes research plans of 19 of the most intensive Major Users of the Facility, documents the inadequacies of the present equipment, and details the benefits the new instruments will convey. The proposed instrumentation is shown herein to be essential to the Major Users' research plans, and will also play a major role in education and professional training on the Davis campus.