Incorporating Gas Chromatography/Mass Spectrometry into the Undergraduate Curriculum

该项目将气相色谱/质谱仪(GC/MS)整合到整个化学课程中。在实验室入门课程中，在实验室演示层析之后，学生使用GC/MS通过分离材料的保留时间和相对分子质量来鉴定液体混合物。在有机化学实验室，学生学习更多的气相色谱和质谱学理论，并使用GC/MS分析他们合成或接收的各种材料。GC/MS还允许在这门课程中有更多种类的特殊项目。在分析化学中，学生可以开始独立使用GC/MS。他们可以开发一种程序来分析土豆中的杀虫剂，以及一种程序来分析在模拟太空条件下材料排放的气体。在光谱学过程中，用GC/MS获得的质谱图可以用来说明影响质谱图的实验参数。在生物化学实验室，学生使用该仪器来测定从天然材料中分离和制备的脂肪酸酯的组成，并使用GC/MS来确定蛋白质的氨基酸组成。在高级实验室，GC/MS允许对研究级合成产品和更难的未知物进行充分表征。该仪器可以进一步推进一些本科研究项目，并允许其他项目的启动。可为当地化学界赞助一系列关于质谱学的研讨会，使用来自当地行业和当地大学的演讲者。*

This project incorporates a gas chromatograph mass spectrometer (GC/MS) throughout the chemistry curriculum. In the introductory laboratory courses, after a laboratory illustrating chromatography, students use the GC/MS to identify a mixture of liquids using the retention times and molecular weights of the separated materials. In organic chemistry laboratory, students learn more of the theory of gas chromatography and mass spectrometry and use GC/MS in the analysis of a variety of materials they synthesize or receive. A GC/MS also permits a wider variety of special projects in this course. In analytical chemistry, students can begin using the GC/MS independently. They can develop a procedure to analyze potatoes for pesticides and a procedure to analyze gases that are emitted from materials in simulated space conditions. In the spectroscopy course, mass spectra taken by GC/MS can be used to illustrate the experimental parameters that affect mass spectra. In biochemistry laboratory, students use the instrument to determine the composition of fatty acid esters isolated and prepared from naturally occurring materials, and they use the GC/MS to determine the amino acid composition of a protein. In senior laboratory, the GC/MS permits research-level synthesis products and more difficult unknowns to be fully characterized. The instrument can further some undergraduate research projects and permit other projects to be started. A series of seminars on mass spectrometry can be sponsored for the local chemistry community using speakers from local industry and local universities. *