Transmembrane Signaling by Receptor Protein Kinases in Plants

摘要9809884沃克这项研究旨在了解环境因素如何与植物中的受体相互作用，从而影响植物的生长和发育。因为植物必须适应不断变化的环境，所以重要的是要了解信息是如何在细胞之间传递的，以及植物细胞是如何引起反应的。生物信息的这种感知、传输和处理的过程被称为信号转导。这项建议中的研究着眼于植物质膜受体与蛋白激酶活性的相互作用，已被发现与蛋白质磷酸酶相互作用。这里要测试的假设是，这种磷酸酶使激活的受体去磷酸化，并关闭信号反应。信号受体的调控是生物学研究的一个重要而活跃的领域，这些研究将为这一领域提供重要的信息。*这项拨款的研究着眼于对植物受体的调节，这些受体对环境因素做出反应，并影响植物的生长和发育。这些研究将更好地了解植物对细胞外信号的反应的分子基础。

Abstract 9809884 Walker This research is aimed at understanding how environmental factors interact with the receptors in plants to influence plant growth and development. Because plants must adapt to an ever-changing environment it is important to understand how information is transmitted between cells and how a response is evoked in the plant cell. This process of perception, transmission and processing of biological information is known as signal transduction. The research in this proposal is looking at the interaction of a plant plasma membrane receptor with protein kinase activity, which has been found to interact with a protein phosphatase. The hypothesis to be tested here is that this phosphatase dephosphorylates the activated receptor and turns off the signaling response. The regulation of signaling receptors is an important and active area of biological research, and these studies will provide important information in this area. *** The research in this grant is looking at the regulation of plant receptors which respond to environmental factors and affect plant growth and development. These studies will provide a better understanding of the molecular basis of the response of plants to extracellular signals.