U.S.-Germany Cooperative Research: The Light-Induced, Charge-Separated State of Reaction Centers from Rhodobacter Sphaeroides

9981613朱该奖项支持朱棣文和一名来自佛蒙特大学和州立农业学院的研究生与德国法兰克福马克斯普朗克研究所的Guenter Fritzsch合作进行的研究。该合作将使用x射线晶体学来确定由于电荷分离导致的蛋白质构象的变化，这种变化驱动了细胞膜上的能量转移。光诱导、电荷分离态的高分辨率结构将揭示负责电荷传导和结构稳定性的精确构象变化。通过研究温度和光照波长对结构的影响，他们将能够解决生物分子中电子转移和光合作用的动力学和功能问题。此次合作还将包括来自多特蒙德马克斯普朗克研究所的Ilme Schlichting的贡献。

9981613ChuThis award supports Kelvin Chu and a graduate student from the University of Vermont, and State Agricultural College in a collaboration with Guenter Fritzsch of Max Planck Institute in Frankfurt, Germany. The collaboration will use x-ray crystallography to determine the changes in protein conformation that occur as a result of the charge separation which drives energy transfer across cell membranes. A high-resolution structure of light-induced, charge -separated states will reveal the precise conformational changes responsible for charge conduction and stability of the configuration. By studying the structure as a function of temperature and illumination wavelength, they will be able to address issues concerning the dynamics and function of electron transfer and photosynthesis in biomolecules. The collaboration will also include contributions from Ilme Schlichting of the Max Planck Institute in Dortmund.