FASEB Conference on Nucleic Acid Enzymes: Structures, Mechanisms and Novel Applications; June 18-22, 2000, Saxtons River, Vermont

这次会议将集中于作用于DNA和RNA的酶的结构、机制、生物学作用和实际应用。会议旨在吸引在结构生物学、生物化学和细胞生物学方面具有专业知识的广泛的跨学科科学家小组。这次会议将是美国实验生物学学会联合会(FASE B)在核酸酶学领域主办的第四次会议；最近一次是在国家科学基金会的支持下于1998年举行的。作用于核酸的新酶的发现的爆炸性速度，从高分辨率结构分析中涌现出的丰富的机械信息，以及DNA和RNA酶在生物技术中的核心作用，这些都是使下一次FASEB 2000会议非常及时和具有专题意义的因素。科学计划将包括由杰出特邀演讲者进行的九次口头陈述。会议的主题包括以下领域：(1)DNA修复酶；(2)DNA和RNA聚合酶；(3)转座和重组；(4)DNA和RNA修饰酶；(5)解旋酶和依赖核酸的NTPase；(6)RNA和DNA催化剂；(7)裂解和降解酶；以及(8)核酸酶的新应用和基因组学对酶系统进化的新见解。组织者招募了主要的调查人员担任这些会议的讨论负责人。该计划还将包括每天的海报发布环节。这次会议旨在强调参与DNA新陈代谢的酶与RNA世界中的酶之间的相似之处和差异。因此，该计划已经进行了配置，以便大多数会议将包括关于RNA和DNA交易的演讲。会议的亲密形式旨在促进从事RNA和DNA酶研究的研究人员之间的信息和思想的自由交流-从而加快这两个领域的研究。这样的研究增强了我们对自然世界的了解，从而提高了我们利用自然世界更大地造福社会的能力。所有与会者将被要求展示关于他们的研究的海报。为鼓励初级科学家的职业发展，将从研究生和博士后学员队伍中挑选六名优秀海报进行口头演示。NSF的财政支持将专门针对六名初级科学家，并将用于支付上述会议的费用。

This conference will focus on the structures, mechanisms, biological roles, and practical applications of enzymes that act on DNA and RNA. The meeting aims to attract a broad cross-disciplinary group of scientists with expertise in structural biology, biochemistry, and cell biology. This meeting will be the fourth sponsored by the Federation of American Societies of Experimental Biology (FASEB) in the areas of nucleic acid enzymology; the most recent in this series was held in 1998, with support from the National Science Foundation. The explosive pace of discovery of new enzymes that act on nucleic acids, the wealth of mechanistic information emerging from high resolution structural analysis, and the central role of DNA and RNA enzymology in biotechnology are factors that make this next FASEB 2000 meeting extremely timely and topical. The scientific program will consist of nine sessions of oral presentations by distinguished invited speakers. The subjects of the sessions include the following areas: (1) DNA repair enzymes; (2) DNA and RNA polymerases; (3) Transposition and recombination; (4) DNA and RNA modification enzymes; (5) Helicases and nucleic acid-dependent NTPases; (6) RNA and DNA catalysts; (7) Cleavage and degradative enzymes; and (8) New applications for nucleic acid enzymes and new insights from genomics into the evolution of enzyme systems. The organizers have recruited leading investigators to serve as discussion leaders for these sessions. The program will also include daily poster sessions. The conference aims to highlight the parallels and differences between enzymes involved in DNA metabolism and those of the RNA world. Hence, the program has been configured so that most sessions will include talks on both RNA and DNA transactions. The intimate format of the conference is designed to promote free exchange of information and ideas among researchers who work on RNA and DNA enzymes - thereby expediting research in both fields. Such research enhances our understanding of the natural world and thus our ability to use it for the greater benefit of society. All attendees will be asked to present posters on their research. To encourage career development of junior scientists, six outstanding posters from the ranks of graduate students and post-doc attendees will be selected for oral presentations. Financial support from NSF will be targeted specifically to the six junior scientists and will also be used to defray expenses for the sessions listed above.