Rational Design of Supramolecular Assemblies Via Incommensurate Geometries and Coordination Numbers

化学系无机，生物无机和有机化学项目的这个奖项支持了Kenneth N. Raymond，加州大学伯克利分校化学系的研究员，通过金属配位键组装成超分子簇。该项目将集中在扩大的主体体积簇的合成，超分子簇的形成和重排，超分子主体对客体分子反应性的控制。它的目标是 精确定义什么可以被编程到配体中的研究， 预定的对称性为基础的联系，并利用这一点开发新的化学基于超分子自组装。 四面体、立方体和 将合成十二面体，其中金属离子在顶点，有机连接基沿着边。 在这项工作中开发的基于对称性的原则将普遍适用于其他纳米结构的制备。系统地制备具有受控形状和孔腔的非常大的分子的能力将被利用来催化化学反应。

This award from Inorganic, Bioinorganic, and Organometallic Chemistry Program of the Chemistry Division supports research of Professor Kenneth N. Raymond, Department of Chemistry, University of California at Berkeley into superamolecular clusters assembled by mean of metal-ligand coordinate bonds. The project will focus on the synthesis of expanded host-volume clusters, the formation and rearrangement of supramolecular clusters, the control of guest molecule reactivity by supramolecular hosts. It is the goal of the research to precisely define what can be programmed into a ligand in terms of predetermined symmetry based linkages and to exploit this to develop new chemistry based on supramolecular self-assembly. Large, supramolecular structures of tetrahedra, cubes and dodecahedra will be synthesized with metal ions at the vertices and organic linkers along the edges. Symmetry-based principles developed in this work will be generally applicable to the preparation of other nanostructures. The ability to systematically prepare very large molecules with controlled shapes and pore cavities will be exploited to catalyze chemical reactions.