Acquisition of a Console for a 400 MHz NMR Spectrometer

根据化学研究仪器和设施（CRIF）计划的这份合同，威廉·马什·莱斯大学化学系将获得一台400 MHz核磁共振光谱仪的控制台。该设备将使研究人员能够进行以下研究：a)茂金属-铝氧烷相互作用；B)三金属分子的溶液结构表征；c) 13族汞配合物催化有机和有机金属芳香族化合物中易氢/氘交换的产物分布和相对产率表征；D)用于电子、光子和模板自我复制应用的精确长度和结构的分子合成；E)开发新的有机合成方法和天然产物的全合成；F)金属原子化学；G)新型芳系化学；H)利用重组微生物合成萜烯；g)含有非天然核苷酸的单链DNA低聚物的合成。核磁共振（NMR）波谱是化学家用来阐明分子结构的最有力的工具。它用于识别未知物质，表征分子内原子的特定排列，以及研究溶液中分子之间相互作用的动力学。获得最先进的核磁共振光谱是必不可少的化学家谁正在进行前沿研究。这些核磁共振研究的结果将对包括材料化学和生物化学在内的许多领域产生影响。

With this award from the Chemistry Research Instrumentation and Facilities (CRIF) Program, the Department of Chemistry at William Marsh Rice University will acquire a console for a 400 MHz NMR Spectrometer. This equipment will enable researchers to carry out studies on a) metallocene-alumoxane interactions; b) solution structural characterization of tri-metallic molecules; c) characterization of the product distribution and relative yield from the facile hydrogen/deuterium exchange in organic and organometallic aromatic compounds catalyzed by Group 13-mercury complexes; d) synthesis of molecules of precise length and constitution for electronic, photonic, and template self-replication applications; e) development of novel organic synthetic methods and the total synthesis of natural products; f) metal atom chemistry; g) chemistry of novel aromatic systems; h) terpene biosynthesis using recombinant microorganisms; and g) the synthesis of single-stranded DNA oligomers containing nonnatural nucleotides. Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometry is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in a number of areas including materials chemistry and biochemistry.