Console solid-state NMR 400 MHz

拟议更换现有400兆赫固态核磁共振光谱仪的控制台，包括用于测量扩散系数的梯度系统的控制器，是马丁-路德大学哈雷物理研究所核磁共振系的中心研究仪器。该仪器用于解决软凝聚物质的结构和动力学领域的研究问题，特别是在合成和生物聚合物系统以及类脂膜中。在合成聚合物领域，人们使用多种核磁共振方法(1H时域核磁共振、弛豫法、宽线谱、多维核磁共振、高分辨固态核磁共振、扩散法)来探索结构-动力学-性质关系，而固态蛋白质主要是高分辨和多维方法的领域。合成聚合物领域正在进行的项目涉及拉伸聚合物玻璃中的取向有序化，不同类型聚合物网络和凝胶中的网络网状结构和传输现象，聚合物纳米复合材料中的动力学，以及半结晶聚合物中的结构形成和动力学。在生物大分子领域，人们关注的焦点是瞬时组装蛋白质(包括来自眼晶状体的蛋白质)中的旋转和平移扩散以及固态蛋白质的整体摇摆运动。在脂膜中，分子动力学具有高精度的特征，并与计算机模拟相匹配；此外，它们还作为聚合物结晶的限制几何。计划中的未来项目将致力于液-液相分离的全球蛋白质动力学，蛋白质动力学和固态堆积耦合工作的扩展，填充弹性体共混物的微观结构和老化行为的阐明，缔合聚合物中的松弛机制，新聚酯和玻璃体的动力学和结晶，以及更复杂的生物膜系统中的动力学。

The proposed replacement console for an existing 400 MHz solid-state NMR spectrometer including controls for a gradient system for the measurement of diffusion coefficients is the central research instrument of the NMR department at the Institute of Physics of the Martin-Luther-University Halle. The instrument is used to address research questions in the area of structure and dynamics in soft condensed matter, especially in synthetic and biological polymer systems as well as in lipid membranes. In the area of synthetic polymers, structure-dynamics-property relations are explored using a combination of NMR methods (1H time-domain NMR, relaxometry, broad-line spectroscopy, multidimensional NMR, high-resolution solid-state NMR, diffusometry), while proteins in the solid state are primarily the domain of high-resolution and multidimensional methods. Ongoing projects in the field of synthetic polymers deal with orientational ordering in stretched polymer glasses, network mesh structure and transport phenomenon in different types of polymer networks and gels, dynamics in polymer nanocomposites, and structure formation and dynamics in semi-crystalline polymers. In the field of biological macromolecules, the focus is on rotational and translational diffusion in transiently assembling proteins (including those from the eye lens) and global rocking motions of proteins in the solid state. In lipid membranes, molecular dynamics are characterized with high accuracy and matched with computer simulations; furthermore, they serve as confining geometry for polymer crystallization. Planned future projects will pursue global protein dynamics upon liquid-liquid phase separation, an extension of work on the coupling of protein dynamics and packing in the solid state, elucidation of the microstructure and aging behavior of filled elastomer blends, relaxation mechanisms in associating polymers, the dynamics and crystallization of new polyesters and vitrimers, and dynamics in more complex biological membrane systems.