CONFERENCE: 2001 Cold Spring Harbor Laboratory Trosine Phosphorylation and Cell Signalling Conference to be held May 16-20, 2001 in Cold Springs Harbor, NY

酪氨酸磷酸化与细胞信号传导冷泉港实验室会议2001年5月16日- 20日现在认为酪氨酸残基上蛋白质的磷酸化是控制诸如生长和增殖、分化、细胞骨架功能和细胞周期等基本细胞过程的重要因素。目前，蛋白酪氨酸激酶（PTKs）和蛋白酪氨酸磷酸酶（PTPs）的结构、调控和功能的研究取得了显著进展，它们的协调作用决定了细胞磷酸化酪氨酸的水平。第七届“酪氨酸磷酸化和细胞信号传导”会议的目标是提供一种整合ptk和PTPs研究的形式，以帮助参与者了解他们的结果如何对整体“大局”做出贡献。这些课程将围绕生理过程和细胞功能进行组织，而不是围绕特定类别的酶，以便尝试提供生物学背景。除了Joseph Schlessinger和Jack Dixon的主题演讲外，所有演讲者都将从提交的摘要中选择。这将把重点放在鼓励研究生、博士后研究员和年轻的独立研究者发表演讲上。它还应有助于介绍最近和“最热门”的结果。预计将有300- 350人出席。大约60人将作口头报告，多达160人将展示海报。NSF基金将使更多的年轻研究者能够参与其中，特别是那些尚未获得独立资助的年轻研究者。本次会议对ptk和PTPs研究的整合，将重点放在这些酶的生物学作用上，将在整个领域产生一种凝聚力和交流感。

Tyrosine Phosphorylation and Cell Signaling Cold Spring Harbor Laboratory Conference May 16 - 20, 2001The phosphorylation of proteins on tyrosyl residues is now recognized to be an essential element in the control of such fundamental cellular processes as growth and proliferation, differentiation, cytoskeletal function and the cell cycle. We are currently witnessing an outstanding period of progress in characterizing the structure, regulation and function of both protein tyrosine kinases (PTKs) and protein tyrosine phosphatases (PTPs), the coordinated action of which governs the levels of cellular phosphotyrosine. The objective of the Seventh Meeting on "Tyrosine Phosphorylation and Cellular Signalling" is to provide a format in which the study of PTKs and PTPs will be integrated to help participants see how their results contribute to the overall "big picture." The sessions will be organized around physiological processes and cellular functions, rather than around particular categories of enzymes, so as to try and provide a biological context. With the exception of the Keynote Addresses by Joseph Schlessinger and Jack Dixon, all speakers will be selected from submitted abstracts. This will allow emphasis to be placed on encouraging graduate students, post-doctoral fellows and young independent investigators to present talks. It also should facilitate the presentation of the most recent and "hottest" results. An attendance of 300- 350 is anticipated. Approximately 60 will give oral presentations and up to 160 will present posters. NSF funds will enable more young investigators to participate, especially those who do not yet have independent funding. The integration of research on PTKs and PTPs at this meeting, placing emphasis on the biological roles of these enzymes, will engender a sense of cohesiveness and communication across the field.