Protein Logic

化学，分子和细胞生物科学，化学运输系统，计算机通信研究以及实验和综合活动的部门支持伊利诺伊大学厄巴纳-香槟分校的这一多部门奖项。这个纳米跨学科研究团队（NIRT）奖是纳米科学与工程计划的一部分。 在该项目下，由Joseph Lyding担任首席研究员的跨学科团队将开发基于蛋白质的逻辑芯片，该芯片将生化反应与传统的微制造硅基电子器件（如金属氧化物半导体（MOSFET））之间的接口，利用生物复杂性和电子速度。 这些蛋白质接口MOSFET将有助于创建原子精确的蛋白质阵列，以用作细胞非线性/神经网络，这反过来将有助于克服目前晶体管技术小型化的100 nm限制。 K-12系统中的工业合作和外展计划将是该项目的一部分。根据该奖项，将开发有序和原子精确的蛋白质阵列，这些蛋白质阵列将生物化学反应与传统的微加工硅基电子器件连接起来。强有力的工业合作将有助于这一科学的工业发展和技术转让。 此外，该研究计划将为从K-12到博士后的学生提供材料化学，蛋白质化学和电子学的多学科教育和培训机会。

Divisions of Chemistry, Molecular and Cellular Biosciences, Chemical Transport Systems, Computer-Communications Research, and Experimental and Integrated Activities support this multidivisional award to University of Illinois Urbana-Champaign. This Nanoscale Interdisciplinary Research Team (NIRT) award is part of the Nanoscale Science and Engineering program. Under this project, an interdisciplinary team with Joseph Lyding as the principal investigator will develop protein-based logic chips that interfaces between biochemical reactions and conventional microfabricated silicon-based electronics such as metal-oxide semiconductor (MOSFETs) taking advantage of biocomplexity and electronic speed. These protein interfaced MOSFETs will help to create atomically accurate protein arrays to function as cellular nonlinear/neural network, and this in turn will help to over come the 100 nm limit in miniaturization of the present transistor technology. Industrial collaborations and outreach programs in the K-12 system will be part of the project. Under the award, ordered and atomically accurate protein arrays that interfaces between biochemical reactions and conventional microfabricated silicon-based electronics will be developed. Strong industrial collaboration will help in the industrial development and technology transfer of this science. In addition, the research program will provide multidisciplinary education and training opportunities in materials chemistry, protein chemistry and electronics to students from K-12 to post doctoral candidates.