MRI: Acquisition of a Core Automated DNA Sequencing Facility

抽象的。 NSF 0116165收购核心自动DNA测序设备一笔赠款已授予彼得F。斯特劳布，布赖恩J罗杰森博士和卡伦P约克博士的理查德斯托克顿学院的新泽西建立一个DNA测序设施。 新的核心遗传分析设施一旦建立，将能够对遗传数据进行自动DNA测序、DNA片段分析和综合计算机分析。 该设施将用于支持学生的本科研究，教师的研究，并加强在斯托克顿学院的分子和遗传生物科学的教学。该赠款获得的主要仪器是一个自动DNA测序仪。 用于运行测序反应的其他仪器、专用软件包和用品已获得资助，以增加该设施的研究能力。 为了吸引大量的学生和教师，在赠款的前三年将支持两个合作示范项目。 第一个项目将使用测序和DNA片段分析来识别地下含水层中的细菌。 研究结果将为大规模地热能利用的研究（如斯托克顿学院）提供有用的信息。 第二个项目将从冬比目鱼基因文库中产生短DNA序列，以支持渔业研究。 这两个项目都邀请学生和教师之间的多用户大规模合作，并将产生对科学界立即有用的知识。 这个项目有可能改变教学和研究的方式是在一个主要的本科院校，如新泽西州的理查德斯托克顿学院进行。 该补助金支持一个专注于遗传学师生合作研究的设施。 这些机会对于培养本科研究生非常重要，因为医学，制药和生物技术一直是经济中最重要的部门之一，其增长直接受到生物技术革命性进步的影响（如DNA测序）在过去二十年中。

Abstract. NSF 0116165Acquisition of a Core Automated DNA Sequencing FacilityA grant has been awarded to Dr. Peter F. Straub, Dr. Brian J. Rogerson and Dr. Karen P. York of the Richard Stockton College of New Jersey to setup a DNA Sequencing Facility. The new Core Genetic Analysis Facility, once established, will enable automated DNA sequencing, DNA fragment analysis and integrated computer analysis of genetic data. This facility will be used to support student undergraduate research, faculty research and to enhance teaching in the Molecular and Genetic Biosciences at Stockton College.The main instrument acquired by the grant is an automated DNA Sequencer. Other instruments useful in running the sequencing reactions, specialized software packages, and supplies have been funded to add more research capabilities to the facility. To involve large numbers of students and faculty, two collaborative demonstration projects will be supported during the first three years of the grant. The first project will use sequencing and DNA fragment analysis to fingerprint and identify bacteria in subsurface aquifers. The results will provide information helpful to the study of large-scale geothermal energy use (such as at Stockton College). The second project will generate short DNA sequences from libraries of winter flounder genes in support of fisheries research. Both of these projects invite multi-user large-scale collaboration among students and faculty and will produce knowledge that is immediately useful to the scientific community. This project has the potential to transform the way that teaching and research are performed at a primarily undergraduate college like Richard Stockton College of NJ. The grant supports a facility that focuses on collaborative student-faculty research in Genetics. These opportunities are important for training undergraduate research students since Medicine, Pharmaceuticals and Biotechnology have been among the most important sectors of the economy whose growth has been directly influence by the revolutionary advancement in biological technologies (like DNA sequencing) over the past twenty years.