Organometallic Reactions Relevant to the Functionalization of Alkanes

Karen Goldberg，华盛顿大学化学系，由无机、生物无机和有机金属化学项目资助，主要研究烷烃C-H键的选择性活化和功能化。她将研究铂催化烷烃氧化的机理、能量学、反应步骤的要求和范围。研究的反应包括铂中心C-H和C-O键的氧化加成/还原消除以及铂配合物与二氧的反应。烷烃的选择性活化和功能化是有机金属化学研究的一个重要方向。与目前的工艺相比，直接从天然气和其他烷烃储备中生产有用的化学品将具有显著的经济和环境优势。学生和博士后也将接受合成、表征、动力学和机理研究方面的重要技能培训。

Karen Goldberg, Department of Chemistry, University of Washington, is supported by the Inorganic, Bioinorganic and Organometallic Chemistry Program for her studies on the selective activation and functionalization of the C-H bonds of alkanes. She will conduct studies of the mechanisms, energetics, requirements and scopes of reaction steps involved in platinum catalyzed alkane oxidation. Reactions to be investigated include the oxidative addition/reductive elimination of C-H and C-O bonds at platinum centers and reactions of platinum complexes with dioxygen.The selective activation and functionalization of alkanes is a major goal in organometallic chemistry. The production of useful chemicals directly from natural gas and other alkane reserves would have significant economic and environmental advantages over current processes. Students and postdoctoral associates will also be trained in important skills of synthesis, characterization, kinetics and mechanistic studies.