Postdoctoral Research Fellowship in Biological Informatics for FY 2002

这一行动为2002财政年度的NSF生物信息学博士后研究奖学金提供资金。 该奖学金支持在生物学和信息，计算，数学和统计科学的交叉点博士后水平的研究和培训。该研究金的目标是向一名青年科学家提供培训，为从事研究和教育相结合的生物信息学职业做准备。在所有职业级别上对生物信息学培训的需求日益增加，预计通过这些研究金培训的研究员将在培训未来的劳动力方面发挥重要作用，该研究金的研究和培训计划题为“从多物种基因谱系的形状推断基因的进化重要性。“据预测，与早期物种的分歧有因果关系的基因座具有物种内单系的基因树，并与物种的遗传一致。本研究发展了基于聚结的概率模型来描述多物种基因谱系的形状。 这些模型正被应用于基因组序列数据，以确定可能涉及物种分歧的基因座。

This action funds an NSF Postdoctoral Research Fellowship in Biological Informatics for FY2002. The fellowship supports research and training at the postdoctoral level at the intersection of biology and the informational, computational, mathematical, and statistical sciences. The goal of the fellowship is to provide training to a young scientist in preparation for a career in biological informatics in which research and education will be integrated. There is an increasing need for training in biological informatics at all occupational levels, and it is expected that Fellows trained through these fellowships will play important roles in training the future workforce.The research and training plan for this fellowship is entitled "Inferring evolutionary importance of genes from the shapes of multi-species gene genealogies." It is predicted that loci causally involved in divergences of incipient species have gene trees that are monophyletic within species and concordant with species phylogenies. This research develops coalescent-based probabilistic models to describe shapes of multi-species gene genealogies. These models are being applied to genomic sequence data to identify loci potentially involved in species divergences.