NIRT: Nanoengineered shells for encapsulation and controlled release

0210298Lvov本提案是对NSF 01-157类纳米科学与工程倡议的响应。该项目旨在合成纳米级功能材料及其在医疗和生物领域的应用潜力。研究小组已经组建，以开发基于自组装原理的有用复合材料的制造方法，成员包括化学、物理、工程、生物材料和药理学的研究人员。要详细描述的纳米包埋方法包括形成具有限定组成和尺寸的胶体核，以及制备提供所需稳定性、渗透性、兼容性、核材料的释放以及催化或亲和性的外壳。

0210298LvovThis proposal was received in response to the Nanoscale Science and Engineering Initiative, NSF 01-157, category NIRT.This project targets the synthesis of nanoscale functional materials and their potential for applications in medical and biological areas. The research team has been assembled to develop methods for fabrication of useful composite materials based on principles of self-assembly and includes researchers in chemistry, physics, engineering, biomaterials, and pharmacology. The nano-encapsulation method to be elaborated involves the formation of a colloidal core with defined composition and size, and the preparation of an outer shell providing the required stability, permeability, compatibility, release of core material, and catalytic or affinity properties.