CAREER: Gold Nanoparticles with Single Copy of Functional Groups - Synthesis and Study

本CAREER项目的目标是通过独特的固相合成方法，开发一种具有单表面官能团的金纳米颗粒合成的通用方法。这些金纳米颗粒可以被视为“扩展”分子，传统的合成化学可以在它们上面进行，以制造复杂的纳米颗粒“聚合物”和“大分子”。与广泛研究的自组装技术相比，我们的研究将展示一种使用传统合成化学来开发新型纳米材料和“合成”纳米电子设备（如量子细胞自动机）的替代方法。该项目的成功将为纳米粒子和纳米材料领域开辟一个全新的方向。围绕这一研究目标，将开展两项教育活动，将以下先进的化学研究和工业应用带到学生的培训中：(1)将开发一门新的研究生课程，题为“超分子化学主题”；(2)透过合作研究及邀请知名工业科学家成为本署工业顾问委员会的成员，建立业界与纳米科技的紧密联系。建立强调纳米技术和工业的研究和教育联系将促进技术转让，并为研究生和本科生培训带来独特的机会。拟议的CAREER研究项目将开发一种新的方法来合成具有独特化学结构的金纳米颗粒。金纳米粒子是纳米电子器件和纳米计算机发展中最重要的纳米材料之一。这一研究领域的发展不仅对基础科学的进步具有重要意义，而且具有巨大的潜在商业价值。纳米电子学和纳米器件研究的一个“瓶颈”是如何将纳米粒子操纵和组装成极其复杂的集成电路（IC）。我们的研究为通过传统的化学反应“合成”复杂的纳米器件和纳米电子学提供了一种创新的方法。

The goal of this CAREER project is to develop a general methodology for the synthesis of gold nanoparticles with single surface functional groups through a unique solid phase synthesis approach. These gold nanoparticles can be treated as "extended" molecules and traditional synthetic chemistry can be conducted on them to make complex nanoparticle "polymers" and "macromolecules." In contrast to the extensively studied self-assembling techniques, our research will demonstrate an alternate approach of using traditional synthetic chemistry to develop novel nanomaterials and to "synthesize" nanoelectronic devices such as quantum cellular automata. The success of this project will open a completely new direction in the nanoparticle and nanomaterial field. Centered on this research goal, two educational activities will be pursued to bring the following advanced chemistry research and industrial applications to student training: (1) a new graduate course entitled "Topics in Supramolecular Chemistry" will be developed; and (2) a strong link will be established among nanotechnology industries through collaborative research and by inviting renowned industrial scientists to become members of the Industry Advisory Board in our department. The establishment of a research and education link emphasizing nanotechnology and industry will facilitate technology transfer and bring unique opportunities to graduate and undergraduate training. %%%The proposed CAREER research project will develop a novel methodology to synthesize gold nanoparticles with unique chemical structures. Gold nanoparticles are among one of the most important nanomaterials for nanoelectronic devices and nanocomputer development. The development of this research area is not only important for the advancement of basic science, but also holds enormous potential commercial value. A "bottleneck" in nanoelectronics and nanodevice research is how to manipulate and assemble nanoparticles into extremely complicated integrated circuits (IC). Our research provides an innovative approach to "synthesize" complex nanodevices and nanoelectronics though traditional chemical reactions.