NER: Semiconductor Quantum Dot-Based Artificial Enzymes. Rational Design and Development

项目编号：0403262机构：密歇根州理工大学项目负责人：刘健题目：NER：基于半导体量子点的人工酶的合理设计与开发本项目由NSF/NER项目资助，旨在通过模拟非蛋白环境下天然酶的活性来寻求水溶性半导体量子点（QDs）的新功能。在此方案下，纳米复合材料光催化人工酶通过在量子点上的人工底物识别位点施加光诱导的电子、能量和几何变化来模拟酶的调节机制和选择性化学。将模拟酶的几个关键特征，以了解我们如何控制这些基于量子点的非蛋白酶的活动，利用光作为良性太阳化学过程的热力学驱动力来源。

PROPOSAL NO: 0403269INSTITUTION: Mich Technological UnivPRINCIPAL INVESTIGATOR: Liu , JianTITLE: NER: Semiconductor Quantum Dot-Based Artificial Enzymes Rational Design and DevelopmentThe goal of the proposed work, funded by NSF/NER program, is to seek new functionalities of water-soluble semiconductor quantum dots (QDs) by mimicking the activities of natural enzyme within a non-protein environment. Under such scheme, the nano-composite based photo-catalytic artificial enzymes are designed to mimic the regulation mechanisms and the selective chemistry of enzymes by imposing light-induced electronic, energetic, and geometric changes on artificial substrate recognition sites on QDs. Several key features of enzymes will be mimicked to understand how can we control the activities of these QD-based, non-protein enzymes in using light as a source of thermodynamic driving force for benign solar chemical processes.