Nonlinear dynamics of microcantilevers interacting with nanostructures - applications to biomolecular sensing and nanotribology

0409660 -与纳米结构相互作用的微悬臂梁的非线性动力学-生物分子传感和纳米摩擦学的应用该项目探讨了计算和实验的新的动力学现象，使用扫描探针微悬臂梁作为纳米尺度的机械性能传感器。拟议的研究目标的两个应用程序的纳米结构的性能表征的关键重要性：（a）在纳米尺度的摩擦的测量和表征，和（B）生物大分子的机械性能的测量。在这两种情况下，将进行调查，以预测这些纳米级测量应用中的微悬臂梁的振荡。总体而言，该项目将（1）帮助对尖锐粗糙体和感兴趣的纳米结构之间的原子尺度摩擦物理学有基本的了解，特别是在与纳米摩擦学、MEMS和生物分子系统相关的滑动速度方面，（二）帮助开发设计指导方针，有意地调整这些微悬臂梁的振动光谱，以提高它们作为重要生物分子的纳米机械特性传感器的性能，结构蛋白和DNA。最后，研究目标得到了更广泛影响的坚实计划的补充，包括更广泛传播研究成果的具体计划，增加少数民族和代表性不足的群体在研究中的参与，让本科生参与研究，并促进与校园结构生物学和凝聚态物理学社区的跨学科合作。

0409660 - Nonlinear dynamics of microcantilevers interacting with nanostructures - applications to biomolecular sensing and nanotribologyThis project explores computationally, and experimentally novel dynamical phenomena underlying the use of scanning probe microcantilevers as mechanical property sensors at the nanoscale. The proposed research targets two applications of key importance in nanostructural property characterization: (a) the measurement and characterization of friction at the nanoscale, and (b) the measurement of mechanical properties of biological macromolecules. In both cases, investigations will be performed to predict the oscillations of microcantilevers in these nanoscale measurement applications. Overall the project will (1) help develop a fundamantal understanding of the physics of atomic scale friciton betweena sharp asperity and nanostructures of interest, especially in sliding speeds of relevance to nanotribology, MEMS and biomolecular systems, (2) help develop design guidelines to tune intentionally the vibration spectrum of these microcantilevers to enhance their performance as nanomechanical property sensors of important biomolecules such as structural proteins and DNA. Finally, the research objectives are complemented by a solid plan for broader impact including specific plans for broader dissemination of research results, increasing participation of minorites and underrepresented groups in research, involving undergraduates in research, and fostering cross disciplinary collaborations with structural biology and condensed matter physics communities on campus.